Kaine is currently a top pick in Liên Quân, especially for players ranging from Veteran to lower ranks, thanks to his new set of abilities.His passive allows him to constantly stealth from early levels, enabling him to ambush and assassinate enemies, as well as participate in skirmishes effectively.
This crucial aspect is what makes him so popular. Kaine can now easily invade the enemy jungle, scout the map, disrupt, or eliminate high-priority targets of the opposing team. Mastering Kaine in the current version is not overly difficult. Let's delve into the intricacies of this hero through the Liên Quân Skill Series with Mytour.

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Kaine's Abilities
Innate - Blood Seal

This is one of the solid innates for a close-range Assassin like Kaine. Alongside increasing running speed by 20% when approaching a target and 30% attack speed when exiting stealth, Kaine gains enhanced assassination capabilities.
Ability 1 - Blood Crescent

This ability allows Kaine to deliver a powerful shock of physical damage, doubling the damage to enemies with the lowest HP, enabling him to eliminate key enemy targets more effectively.
Ability 2 - Blood Sword

Blood Sword is the only ability with crowd control, allowing Kaine to mark an enemy and stun them for 1 second upon dealing additional damage. Alongside the stunning effect is the ability to regenerate health when marking with ability 2. This is a crucial part of his combo, so use it wisely and combine it with other abilities to successfully assassinate enemies.
Ability 3 - Blood Strike

With the ability to avoid being targeted and deal immense physical damage, this is the most important ability in Kaine's combo. It can help him assassinate targets, disengage from fights effectively, or even dodge damage when used at the right moment.
Rune, Support, and Emblem Setup for Kaine
Rune Setup
- 10 Red Runes III Physical Attack/Armor Pierce
- 10 Purple Runes III Physical Attack/Movement Speed
- 10 Green Runes III Physical Attack/Armor Pierce

This is the optimal rune setup for Kaine at the current moment. A large amount of physical attack combined with armor penetration helps Kaine deal stable damage early in the game. The rune setup also includes a certain amount of movement speed to make our hero more flexible in chasing down key enemy targets.
Support
Since Kaine is a versatile hero in Liên Quân, capable of roaming multiple lanes, he can utilize various supports. Here are some suitable supports for him.
- Jungling: Execution
- Top Lane or Support: Rampage or Flicker
These are all supports that optimize damage output for Kaine when using his combo. Besides Execution, which is mandatory for jungling, bringing Rampage will help him finish off enemies quickly. Flicker is a safer option for him to escape danger if his combo fails.
Emblems
As an Assassin, Kaine needs an emblem set prioritizing damage dealing capabilities. Here is the best choice for him.
- Main Branch (Jungle): Blazing Fire - Onslaught - Devil's Awakening
- Sub Branch (Light): Contrast - Penetration

This emblem set is just enough to help Kaine optimize his strength as it possesses armor penetration, % damage increase, and marks targets upon dealing 3 consecutive damage hits to enemy heroes.
Equipment
As mentioned earlier, Kaine is quite versatile, excelling both in Jungling and laning. Being an Assassin, Kaine's equipment revolves around increasing a substantial amount of physical damage along with armor penetration. Here are the equipment sets for Kaine in various positions.
Jungling:- Soulreaver - Hermes' Select - Muramasa - Omniarms - Fenrir's Tooth - Blade of Eternity

- Hermes' Select - Muramasa - Omniarms - Fenrir's Tooth - Scythe of Death - Aegis

- Fire Stone - Hermes' Select - Muramasa - Omniarms - Fenrir's Tooth - Aegis

As an Assassin with massive damage from his combo skills, prioritize equipping him with items that boost physical attack power such as Muramasa, Fenrir's Tooth... These items also come with secondary effects like increased damage against low HP enemies or enhanced movement speed when disengaging, giving Kaine an advantage in hunting down enemy key players.
The Most Effective Way to Play Kaine
Early Game: If you're in the Jungle position, complete your jungle rotation quickly and gank Dragon lane as soon as possible (preferably starting at the Caesar lane). If you're in the Top or Support position, clear minions fast and then move to Dragon lane to pressure the enemy key players, or disrupt, steal, or slow down the opponent's jungle clear speed. Afterward, return to lane and farm the next wave of minions.
Early game, Kaine is quite strong and the enemy team doesn't have support items yet, so players can take advantage of this time to pressure and gain advantages for the whole team. Also, don't forget to assist the team in controlling major objectives like Dragon or Caesar.

Mid-game phase used to be the golden time for Batman when he had 1-2 major items, and Kaine is no different. Focus on picking off and assassinating enemy key players as much as possible. Move around the map, constantly apply pressure to the opponents, disrupt their team formation, and focus on controlling as many objectives as possible. Use this to increase your gold lead over the enemy and potentially end the game early if conditions permit.
In the late-game phase, when the enemy team starts to acquire defensive items, traps, and Kaine begins to fall off, players need to be more cautious. Be careful with every move and execute skills accurately, or else you could be instantly overwhelmed by the damage from the enemy key players. Prioritize targeting low-health enemies when opportunities arise and even consider sacrificing yourself to secure kills for your team, especially for Marksmen, to give your team a significant advantage in combat.
Conclusion
So, we've thoroughly explored the most effective way to play Kaine in the S3 2023 season. Apply the tactics and equipment suggestions above to optimize the hero's strength and exert pressure on the enemy lineup. Wishing you mastery over this hero.