If you possess an EpiPen auto-injector for severe allergies, it's crucial to dispose of it correctly–even if unused. Improper disposal of EpiPens in household waste can pose risks to people or pets. While regulations for EpiPen disposal vary greatly depending on your location, it's generally advisable to return a used or expired EpiPen to the healthcare provider who prescribed it. They will be knowledgeable about appropriate disposal methods.
Guidelines
Utilizing Used EpiPens

Immediately contact emergency services after using an EpiPen. A severe allergic reaction is a medical emergency. If you're near a hospital and have transportation, head to the emergency room promptly. Otherwise, dial 911 or your local emergency number for ambulance assistance.
- Even if the EpiPen appears effective and you feel fine, seeking immediate medical help is imperative. There may be a recurrence of symptoms or a need for further treatment or medication.
- When contacting emergency services, provide precise details of your exposure and the timing of EpiPen use. If there's a risk of additional exposure, inform them accordingly. This information will assist responders upon arrival.

Secure the used EpiPen in its container, clearly labeled. EpiPens feature built-in needle covers for post-use protection, but handling should still be cautious. Return it to its original box if available, noting the administration date and time on the box's exterior.
- If the original packaging is unavailable, use a permanent marker to note the time on the device's exterior.
- Do not discard the used EpiPen until you've received medical attention. Keep it with you to provide to treating medical personnel.

Hand over the used auto-injector to emergency responders. Providing details of when and how much medication was administered assists emergency responders or ER staff in determining the need for additional doses.
- Medical professionals are trained in proper EpiPen disposal. Typically, after recording the medication amount and time, they dispose of it with medical waste.
Expired EpiPens

Check the EpiPen device for the expiration date. The date on the device itself is generally more accurate than that on the original box. If unable to locate the device's expiration date, use the box's date as a reference or consult a pharmacist.
- Pharmacists can often determine the expiration date if it's not visible on the device.

Replace your EpiPen before it expires. If your country requires a prescription for EpiPens, refill your prescription at least 30 days before expiration to ensure availability.
- Call your pharmacy in advance to ensure EpiPens are in stock. If unavailable and your current EpiPen is nearing expiration, check other pharmacies.
- Request the latest possible expiration date from the pharmacist for longer-lasting use.

Retain your expired EpiPen only as a last resort. Although expired, an EpiPen might still contain sufficient medication to save a life for up to 2 years post-expiration. While relying solely on an expired EpiPen isn't advisable, it can serve as a backup for a few months thereafter.
- Do not use an EpiPen if the liquid appears discolored or contains solid particles, indicating medication destabilization. Observe the liquid through the window on the EpiPen, surrounded by a yellow box labeled 'Replace if solution is discolored.'
- An expired EpiPen may not effectively halt a severe allergic reaction. If only an expired EpiPen is available, contact emergency services and specify its use. Avoid re-administration, even with a valid EpiPen, to prevent overdose.
- Set electronic reminders to track EpiPen expiration and ensure timely replacement. Do not rely solely on expired EpiPens.

Return your expired EpiPen to a healthcare professional. Although equipped with safety caps, discarding an expired EpiPen in household waste isn't recommended. When obtaining a new EpiPen, bring along the expired one to your pharmacist for proper disposal.
- You can also hand over the expired EpiPen to your healthcare provider when renewing your prescription, if not retained as a backup.
Effective Storage

Store your EpiPen in a cool, dry place. To maintain medication efficacy, shield your EpiPen from sunlight and excess moisture. After use, promptly return it to a suitable environment.
- Avoid storing EpiPens in bathrooms due to humidity.
- For work or school, invest in specialized storage cases to maintain optimal conditions. These are available online or through healthcare provider recommendations.
- If your child carries an EpiPen to school, entrust it to the school nurse, who can store it appropriately.

Avoid exposing your EpiPen to extreme temperatures. Keep your EpiPen at room temperature, ideally between 68 and 77 °F (20 and 25 °C). While it can withstand temperatures from 59 to 86 °F (15 to 30 °C), avoid prolonged exposure at the extremes.
- Consider using specialized carriers when outdoors for extended periods to maintain proper temperature. These are available online or through healthcare provider recommendations.
- Avoid storing EpiPens in car glove boxes due to temperature fluctuations, unless in mild climates with stable temperatures and humidity.

Ensure your EpiPen is in your carry-on when flying. When traveling by air, keep your EpiPen in your carry-on luggage and inform flight and security personnel. Never stow your EpiPen in checked baggage, as the cargo hold is unpressurized and could damage the device.
- If traveling to a country where EpiPens require a prescription, obtain a doctor's letter explaining its necessity. Contact your passport agency for requirements before your trip.

Keep the blue safety release cap on until ready to use your EpiPen. EpiPens feature a blue safety cap to prevent accidental injection. Removing it prematurely could lead to unintended discharge. The cap also ensures needle sterility.
- If the safety cap detaches but the EpiPen remains unused, replace it. Place the unit in its carrier tube with the safety release end facing the opening. Carefully press the cap onto the end, avoiding contact with fingers.
Suggestions
Caution
- An EpiPen does not substitute medical treatment. Seek immediate medical help after using an EpiPen, regardless of symptom improvement. A secondary reaction may occur later.