1. Anti-inflammatory supplements
Anti-inflammatory supplements are divided into two main types: steroid anti-inflammatory supplements and non-steroidal anti-inflammatory supplements. Health experts suggest taking anti-inflammatory supplements during the day because based on the pharmacokinetics of these supplements, they will have a stronger anti-inflammatory effect during the day than at night. This is because the body's cortisol hormone levels, which are highest during the day, enhance the effects of anti-inflammatory supplements.

2. Pain relief supplements
Pain relief supplements are divided into 2 main groups: central pain relief supplements and peripheral pain relief supplements. Peripheral pain relief supplements should be taken during the day because they often contain anti-inflammatory agents. Not to mention, some of these supplements also contain caffeine to enhance pain relief effects, which can stimulate and uplift mood, leading to difficulty sleeping if taken in the evening.

3. Diuretic supplements
Diuretic supplements are used to increase the kidney's filtration rate, thereby increasing the amount of urine expelled from the body throughout the day. Diuretic supplements are often used to treat conditions such as hypertension, edema, increased intraocular pressure, or urinary retention, or used to manage certain emergency situations. The function of this type of supplement naturally dictates that they should be taken during the day because if taken in the evening, you will have to deal with nocturnal urination, disrupting sleep or even causing insomnia.

4. Blood sugar lowering supplements
Blood sugar lowering supplements are medications used for individuals with type 2 diabetes (non-insulin-dependent diabetes) - a common condition in middle-aged and older individuals, those who are overweight or obese, or those with a family history of diabetes. Blood sugar lowering supplements are recommended to be taken during the day for easy control of the body's blood sugar levels. If taken in the evening, there is a risk of significantly lowering blood sugar levels during sleep, thereby threatening life.

5. Bowel regulating supplements
Bowel regulating supplements work by increasing bowel motility and enhancing the transport of waste materials within the intestines to facilitate smoother digestion. The majority of cases using bowel regulating supplements aim to treat constipation, cleanse the intestines in preparation for diagnostic endoscopic procedures, or manage certain cases of intoxication. Bowel regulating supplements should be taken during the day because their use stimulates bowel movements and significantly affects sleep if taken in the evening before bedtime.

6. Health care products
Health care products (excluding dietary supplements) often contain various types of vitamins. This type of product provides a lot of energy to the body and stimulates mental alertness. Therefore, it is suitable to take these products during the day to increase efficiency in studying and working. If taken in large amounts at night, health care products can cause stimulation, difficulty sleeping, or prolonged insomnia.

7. Blood pressure lowering supplements
Blood pressure lowering supplements are pills used to treat hypertension. Blood pressure lowering supplements include many groups and various types of pills. Most blood pressure lowering pills are recommended to be taken during the day for convenient monitoring of the treatment's effectiveness and timely management of its side effects or cases of overdose. It is advisable to limit the intake of blood pressure lowering supplements in the evening because when we sleep, our blood pressure tends to drop low and there is a risk of severe hypotension if blood pressure lowering pills are taken before bedtime, which can be life-threatening.

8. Anti-depressant supplements
Anti-depressant supplements are commonly used to treat depression and some other mental health disorders such as anxiety disorders, insomnia, or eating disorders… Anti-depressant supplements are also divided into various groups: Tricyclic antidepressants, MAO inhibitors, or SSRI antidepressants,… Among these groups, SSRI has a strong stimulating effect so it is recommended to take them during the day to maximize the effects of happiness, euphoria, or zest for life for patients. Taking antidepressants at night can lead to side effects such as insomnia or mood elevation affecting sleep quality.

9. Brain-boosting supplements
Brain-boosting supplements are often used to treat conditions such as forgetfulness, memory decline, reduced concentration commonly seen in the elderly, overworked individuals, or those with intellectual developmental delays. Brain-boosting supplements increase blood flow to the brain, enhancing alertness and concentration. Therefore, these supplements should be taken during the day to stimulate efficient work performance, increase enthusiasm, and thereby enhance work quality and productivity.

10. Weight loss supplements
Weight loss supplements are used to reduce weight in overweight or obese individuals by inducing appetite suppression, reducing the absorption of lipids, and lowering cholesterol levels in the blood. Weight loss supplements often contain stimulants, so it is recommended to take them during the day to avoid nighttime insomnia.

