1. Spider
Spider is a predatory invertebrate animal, without a backbone belonging to the class Arachnida; their body has only two parts, eight legs, mouth without chewing jaws, and no wings - the same class as scorpions, ticks.... There are many different types of spiders, some are non-venomous, while the rest are extremely venomous.
Although spiders are small creatures, their venom is extremely harmful and can kill an adult human in just a few minutes. Some common venomous spider species include wolf spiders, black widow spiders, sac spiders, house spiders,... The venom of spider species when entering the human body can cause symptoms such as muscle necrosis, rupture of blood vessels, tissue destruction, respiratory failure, and lead to rapid death.

2. Green Tree Snake
The green tree snakes have long, fang-like teeth, perpendicular to each other, folded along both sides of the lower jaw, only raised when attacked. The venom of green tree snakes contains pre-coagulation enzymes causing uncontrollable bleeding. Additionally, the toxins of the green tree snakes also cause symptoms such as disseminated intravascular coagulation, renal failure, shock, hypoglycemia,...
Their venom contains very potent Hemotoxins. When bitten by a green tree snake, the victim will experience extreme pain at the wound site. The pain will not subside until 24 hours after the snake bite. Within minutes of being bitten, the wound site will swell rapidly, with skin and muscle necrosis. Moreover, the surrounding flesh will quickly die and turn black to clearly show the bite marks.

3. King Cobra
King Cobra, belonging to the cobra family, is one of the most venomous snakes. Most cases of human King Cobra bites occur due to catching or provoking the snake. The venom of King Cobra causes neurological paralysis, drowsiness, unconsciousness, difficulty breathing, leading to respiratory failure, dizziness, hypotension, and death due to cardiac arrest. It is estimated that the amount of venom released in a bite can be fatal to about 20 - 30 adults if not treated.
A large amount of antivenom may be sufficient to reverse the progression of symptoms of envenomation when bitten by a snake. The venom attacks the victim's central nervous system, leading to pain, blurred vision, dizziness, drowsiness, and ultimately paralysis. If the condition becomes severe, the toxin progresses to the circulatory system, causing the victim to fall into a coma. Death quickly occurs due to respiratory failure.
Furthermore, victims may also experience kidney failure according to some experimental bite observations, although this possibility is not common. The bite of a King Cobra can lead to rapid death in just 30 minutes. The venom of King Cobra is even recorded to have the ability to kill a fully-grown elephant within a few hours.

4. Box Jellyfish
Some jellyfish species are harmless, but others contain venom that is 100 times more toxic than that of a cobra snake. The stinging cells containing venom in jellyfish are called nematocysts. The venom of box jellyfish is considered the most dangerous in the world because its toxin attacks the heart, nervous system, and skin cells causing muscle necrosis, cardiac arrest, neurological paralysis, respiratory failure, and rapid death.
Box jellyfish once caused over 5,500 deaths in 1954. This species of jellyfish is found in offshore waters of North Australia and throughout the Pacific - Indian Ocean region. Each tentacle has 5,000 venomous cnidocytes, and the venom they carry is potent enough to 'subdue' 60 people in just a few minutes. According to experts' estimates, over 100 people die each year globally from box jellyfish stings.

5. Scorpion
The venom of some scorpion species can cause their prey or enemies to convulse, froth at the mouth, lose control of urination until death. The venom of scorpions contains Hemiscorpius lepturus, which destroys cells and paralyzes the nervous system. The most lethal scorpion species is Androctonus australis, or the North African fat-tailed scorpion.
With a range of up to 1 meter, their venom can cause temporary or permanent blindness to enemies or prey. Their venom is extremely toxic. Symptoms often include profuse sweating and intense pain, excessive urination, muscle spasms, and cardiac arrhythmias may occur in one-third of cases.

6. Blue-Ringed Octopus
The blue-ringed octopus, scientifically known as Hapalochlaena, carries a potent neurotoxin on its body, which is 1,200 times stronger than cyanide. This species inhabits the coral reefs of the Indian and Pacific Oceans, with venom 50 times more powerful than that of a venomous scorpion.
It is one of the most 'lethal' creatures in the world. There is still no antidote for its venom. Despite its small size, it contains enough venom to kill 25 people within minutes. The venom of the blue-ringed octopus causes neurological paralysis, respiratory failure, cardiac arrest, and rapidly leads to death.
If one consumes the flesh of the blue-ringed octopus, symptoms such as discomfort, flushing, pupil constriction followed by dilation, nausea, diarrhea, weakness in the limbs, and even shivering and numbness in the toes and fingers may appear within 30 minutes to 3 hours after ingestion. If via dermal contact, death can occur within just 10 to 20 minutes.

7. Poison Dart Frog
The majority of frog species do not possess venom, except for some recently discovered species that contain extremely dangerous toxins to humans. These include the blue poison dart frog, golden poison frog, bicolor dart frog, and Bruno's frog. The toxin of poison dart frogs is 20-25 times stronger than that of some species of king cobra. According to many studies, just 1 gram of poison from a poison dart frog is enough to kill 300,000 mice or 80 adult humans.
The golden poison dart frog is one of the most beautiful creatures in the world. They come in yellow, blue, green, and red colors. Despite their beauty, they are extremely toxic. Just one golden poison dart frog like the one in the picture has enough venom to kill 10 adult humans. The toxin called batrachotoxin can cause paralysis and death with only an extremely small amount.

8. Bullet Ant
The bullet ant, scientifically known as Paederus fuscipes Curtis, belongs to the Staphilinidae family (rove beetles), Colleoptera order (beetles), Insecta class (insects), and is one of the most venomous ant species. The venom of the bullet ant is about 12-15 times more toxic than that of a king cobra. However, despite its high toxicity, its small contact area and external exposure are not enough to cause human death like snake venom.
The effects of the bullet ant are not life-threatening, mainly causing damage to the skin. With a large number of bites, the inflamed areas are primarily on the face, neck, arms, legs, hips, and back. The most severe and extensive skin damage occurs in soft skin areas. Symptoms such as swollen, blistering skin may appear 12-36 hours after toxin exposure. If left untreated, inflammation can progress to ulceration, resulting in long, straight wounds or Y-shaped wounds, depending on how they were crushed.

9. Marble Cone Snail
One of the snail species containing dangerous toxins to humans is the Marbled Cone Snail. The toxin produced by this snail can cause itching and pain. However, if exposed to a moderate or large amount of toxin, humans can experience loss of vision, paralysis, respiratory failure, and death. It is noteworthy that there is currently no antidote for the toxin of the Marbled Cone Snail.
Divers are very afraid of encountering the Marbled Cone Snail. They may look beautiful, like other normal snail shells, but when provoked, they strike quickly, and even with diving gloves, the snail's proboscis can penetrate through. A few microliters of toxin in the snail's sting are potent enough to kill at least 10 people.

10. Belcher Sea Snake
One of the deadliest snakes in the world, the bite of the Belcher Sea Snake can kill a person in less than 30 minutes. Fortunately, it is relatively docile and usually does not attack unless provoked. This snake can be found near coral reefs in the Indian Ocean or offshore areas of Thailand and the Philippines.
The Belcher Sea Snake is typically active at night, and they are very gentle, but if threatened, they can become aggressive and strike back. However, in 1/4 of cases, bites do not result in envenomation, as they do not inject venom into the victim's body.
However, these are rare cases because many victims have been attacked by the Belcher Sea Snake, and when venom enters the body, there is no way to cure it, death will quickly occur within minutes. Just a few milligrams of the venom of the Belcher Sea Snake are enough to kill over 1000 people.

11. Anglerfish
The Anglerfish has a large, menacing appearance and is extremely venomous, hence also known as the ruler of toxins beneath the ocean. They often lie motionless or bury half of their body to attract prey. When the venom of the Anglerfish enters the victim's body, the toxin directly affects the motor system, nervous system, cardiovascular system, skeletal system causing muscle necrosis, paralysis, respiratory failure, hypotension, shock, and potential death if not promptly treated.
The venom of the Anglerfish lies within hidden venomous pouches under 13 sharp spines on its back. When humans touch these venomous spines, the venom pouches are compressed, releasing the toxin. The venom pouches are replenished after about 2-3 weeks if the animal goes hunting.

12. Black Mamba Snake
The Black Mamba Snake is found in the vicinity of the Sahara, Africa. Despite being called the black mamba, they are often brown in color, highly aggressive, and lightning-fast attackers. They show no hesitation in attacking humans and can reach heights of up to 4 meters.
The venom of the Black Mamba Snake contains high toxicity, capable of inducing unconsciousness in humans in 45 minutes or less. Without effective antivenom treatment, death typically occurs within 7-15 hours. The venom primarily consists of neurotoxins, notably containing dendrotoxin. The Black Mamba Snake is capable of striking at a considerable distance and sometimes can deliver a series of rapid consecutive bites. Despite their notorious reputation, like most other snakes, they usually try to avoid humans unless threatened or cornered.

13. Pufferfish
The Pufferfish has a bizarre appearance. All types of pufferfish contain tetrodotoxin, a type of neurotoxin. Tetrodotoxin is 1,200 times more toxic than cyanide, and there is currently no antidote. This fish can be consumed, but only when prepared by certified chefs.
The toxin of the pufferfish has high stability. If boiled at 100 degrees Celsius for 6 hours, the toxin only reduces by half; if boiled at 200 degrees Celsius for 10 minutes, the toxin is completely destroyed. Therefore, if cooked normally, pufferfish poisoning can still occur, as the toxin is not completely destroyed. When dried or processed conventionally, the toxin remains undestroyed, leading to poisoning.
Those who ingest pufferfish toxin will experience symptoms of tetrodotoxin poisoning within 5 minutes to 3 - 4 hours, including tingling sensation in the mouth; numbness of lips and tongue, discomfort; followed by fatigue, dizziness, vertigo, sensation of chest tightness, profuse sweating, salivation, foaming at the mouth, slurred speech, difficulty swallowing, flushed face, abdominal pain, nausea, vomiting, tremors, jaw stiffness, tongue stiffness, weakness in lower limbs, constricted pupils. In severe cases, there may be total body paralysis, flaccidity, loss of limb movement, cyanotic skin, decreased body temperature and blood pressure, difficulty breathing, eventually leading to respiratory muscle paralysis, cardiac arrest, and death. The mortality rate is very high (60%) if emergency treatment is delayed.

