Top 9 Highly Trusted Fillers with Superior Quality in Aesthetic Treatments

Xcelens International Pharmaceutical Group, with over 20 years of development and headquartered in Switzerland, is trusted in more than 50 countries worldwide. Known for its proprietary biological regeneration technology using advanced Hyaluronic Acid, Xcelens offers cutting-edge, safe, and high-quality dermal fillers used by doctors, spas, and clinics in non-surgical aesthetics.

Xcelens Filler stands out for its superior bonding properties, ensuring effective volume shaping. Notably, this filler contains no harmful BDDE residues, minimizing the risk of complications. With its advanced Hyaluronic Acid technology, the Xcelens line offers long-lasting, natural-looking results in aesthetic enhancements.

Why Xcelens is a Safe and Effective Filler:

• Utilizes the superior Genyaline cross-linking technology with a stable 3D structure and numerous interwoven cross-links, providing fast and stable shaping, offering support for aging or sagging skin.
• Provides instant skin tightening effects post-injection, with results lasting up to 24 months, compared to 12 months with other fillers.
• High degree of structure with high Hyaluronic Acid concentration, paired with many cross-links, which stimulates natural collagen production.
• High molecular weight and multiple cross-links slow down the breakdown of Hyaluronic Acid, prolonging the filler’s effect.
• Minimal toxicity from cross-linking with butanediol diglycidyl ether (BDDE), reducing the likelihood of allergic reactions.

Available Xcelens Product Lines:

• GenYal Series: Fills moderate wrinkles and tear troughs, creates baby cheeks, and lip contours. No Lidocaine for those sensitive to anesthetics.
• Xcelens Extra (Xcelens Extra 3, Xcelens Extra 4): Fills deeper wrinkles, restores lost volume, and enhances cheekbones and lip volume. Includes Lidocaine for pain reduction, ideal for clients with low pain tolerance.
• Xcelens Extreme HV: Defines facial features, restores volume, and creates facial fat. Sculpting for the nose, chin, and jawline.

Reference Link: https://xcelens.vn/

E.P.T.Q Filler from South Korea is approved by the Ministry of Health and comes with a Vietnamese label, product certification, and complete VAT invoices. E.P.T.Q is a hyaluronic acid-based filler produced in a modern, closed-loop manufacturing system, ensuring safety, high purity, and low BDDE residue that meets Korean Ministry of Health standards. Trusted by cosmetic doctors and clinics both locally and internationally, E.P.T.Q is one of the most widely used Korean fillers.

Why E.P.T.Q is a Safe and Effective Filler:

• Produced and managed within a closed, secure process.
• Stable cross-linking of HA without causing swelling or pain.
• Perfect elasticity and bonding for effective contouring.
• Advanced technology for uniform HA particles.
• Free from harmful catalysts and toxic BDDE residues.
• Manufactured in a sterile environment to prevent side effects.
• Extremely low endotoxin content, under 0.1EU/ml.
• Optimal pH and osmotic pressure, fully compatible with the human body, causing no pain during injection.
• Advanced production techniques minimize injection pressure.

Official E.P.T.Q Product Lines:

• E.P.T.Q S100
• E.P.T.Q S300
• E.P.T.Q S500

Reference Link: https://eptq.co.uk/

Danae Filler is another prominent name featured in Mytour’s list today. Danae Filler has been recognized for its quality and high safety standards by the European Directorate for the Quality of Medicines (EDQM) and the Korea Food and Drug Administration (KFDA).

The main ingredient in Danae is hyaluronic acid, which is used to treat wrinkles and restore volume to areas such as the cheeks, chin, and other facial regions quickly and effectively. You will notice visible results right after use.

Why Danae is a Safe and Effective Filler:

• The hyaluronic acid is produced through a microbial fermentation process, ensuring high safety and long-lasting effects.
• Its unique production process features a “two-step cross-linking” technique and a “purity-enhancing” process that delivers long-term benefits for the skin.

Official Danae Product Lines:

• Danae Line Lidocaine - Blue Box (Medium-sized HA particles)
• Danae Contour Lidocaine - Brown Box (Large-sized HA particles)

Reference Link: https://www.cgbio.co.kr/en/product/aesthetics/danae

LosDeline Filler is a high-quality product from the Czech Republic, leading the way in non-surgical aesthetic treatments. It specializes in contouring facial features as well as supporting breast and buttock enhancement for women. After treatment, users will experience a more confident, radiant appearance with a firmer, fuller, and more attractive physique.

LosDeline is CE-certified and complies with ISO standards, as well as the EU Medical Device Directive 93/42/EC. All manufacturing processes are carried out in sterile environments, with each batch undergoing quality control from three independent laboratories.

Why LosDeline is a Safe and Effective Filler:

• Its main ingredient consists of 98% water, with the remaining 2% being muscle fibers, which makes it highly praised for its safety and health benefits.
• Many aesthetic clinics worldwide, including those in Vietnam, have already incorporated this filler into their beauty enhancement procedures.

Reference Link: https://www.losdeline.com/index.php/en/

Neuramis Filler is a premium and highly acclaimed filler from South Korea. It has been praised by professionals for its safety, non-allergenic properties, and pain-free application. It is widely used in top spas and aesthetic clinics around the world.

Neuramis Filler uses advanced SHAPETM technology, containing hyaluronic acid to treat wrinkles and restore volume to the cheeks, chin, and other areas of the face with exceptional results. You will notice a visible improvement right after treatment.

Why Neuramis is a Safe and Effective Filler:

• SHAPETM technology – Stabilized Hyaluronic Acid & Purification Enhancement. The hyaluronic acid is produced via a microbial fermentation process, ensuring high safety and long-lasting results.
• Neuramis’ unique manufacturing process features a “two-step cross-linking” technique and “purity enhancement,” delivering long-term benefits for the skin.
• It is recognized by the European Directorate for the Quality of Medicines (EDQM) and the Korea Food and Drug Administration (KFDA) for its high quality and safety standards.

Official Neuramis Product Lines:

• Neuramis Volum Lidocaine (Yellow): Nose and chin augmentation.
• Neuramis Deep Lidocaine (Black): Skin rejuvenation, non-surgical face lifting, wrinkle reduction.
• Neuramis Lidocaine (Gray): Treatment for fine wrinkles, lip enhancement.

Reference Link: https://neuramis.uk/

Sardenya Filler is an affordable filler product chosen by many beauty centers. This brand is internationally recognized for its safety and certified by the Korean Ministry of Health. Sardenya Filler is the perfect choice for those looking to enhance their appearance without undergoing surgical procedures or invasive treatments.

Sardenya contains a high concentration of hyaluronic acid, which helps to smooth wrinkles, restore volume, and rejuvenate the skin quickly and safely. The advanced technology and unique two-step cross-linking process used in its production ensure long-lasting aesthetic results after application.

Why Sardenya is a Safe and Effective Filler:

• The main ingredient, hyaluronic acid (HA), is gentle and highly compatible with the body, minimizing the risk of adverse reactions or complications.
• Certified by the European Directorate for the Quality of Medicines (EDQM) and the Korea Food and Drug Administration (KFDA), Sardenya is widely used in many countries, ensuring safety and reliability for users.

Official Sardenya Product Lines:

• Sardenya Deep: A medium-hard filler used for chin sculpting, baby face cheeks, smile lines, and lip enhancement.
• Sardenya Fine: A soft filler suitable for areas like lips, cheeks, smile lines, temples, and the outer corners of the eyes.
• Sardenya Implant: A firm filler used primarily for nose augmentation to enhance the nasal bridge and prevent migration of the filler.

Reference Link: https://www.sardenya.co.kr/

Juvederm is a premium filler distributed by Allergan, one of the top five healthcare corporations in the United States, known for its expertise in biopharmaceuticals and medical technologies. According to aesthetic professionals, Juvederm is a highly effective and safe dermal filler used globally. It is FDA-approved and authorized by Vietnam's Ministry of Health for importation and sale.

The primary ingredient in Juvederm is Hyaluronic Acid (HA), a naturally occurring substance in the human body. Utilizing Hylacross® and Vycross® technology, Juvederm contains up to 24mg/ml of HA— the highest concentration among HA fillers available, making it highly effective at firming the skin and offering long-lasting results for 1 to 2 years.

Why Juvederm is a Safe and Effective Filler:

• Enhances the nasal bridge, defines the chin, plumps the lips, shapes the ears, fills mouth lines, and adds volume to the cheeks.
• Improves up to 90% of wrinkles and restores volume to hollow cheeks and nasolabial folds.
• Non-irritating and free from complications.
• Simple application with no incisions or surgery required.
• Safe, painless, and minimally invasive.

Official Juvederm Product Lines:

• Juvederm Voluma XC: Adds volume beneath the skin’s surface to lift and contour the cheeks.
• Juvederm Ultra XC Plus: Restores elasticity to the skin and smooths wrinkles around the mouth and nose, also known as smile lines.
• Juvederm Ultra XC: Plumps the lips without the need for surgery.

Reference Link: https://www.juvederm.com/

Restylane Filler is a premium product from Galderma, a leading company based in Sweden. The primary ingredient in Restylane is Hyaluronic Acid (HA), a gel that mimics the natural HA found in the body, which helps restore and fill facial imperfections such as the cheeks, chin, eyebrows, and temples, providing a youthful, natural appearance.

With over 40 years of clinical research and more than 20 years of leading the dermal filler market, Restylane Filler has been tested for safety and efficacy by the FDA (U.S.). This assures customers of its safety, eliminating concerns about complications.

Why Restylane is a Safe and Effective Filler:

• Restores facial contours and enhances beauty immediately after injection, with no recovery time required.
• The Hyaluronic Acid in Restylane provides excellent hydration and stimulates collagen production, leaving the skin plump, radiant, and smooth.
• The results last for a long time, ranging from 6 to 12 months, depending on the type of Restylane used and the body's natural absorption rate.

Official Restylane Product Range:

• Restylane Volyme TM, Restylane Defyne TM, and Restylane Kysse TM feature larger gel particles to add volume and enhance contouring.
• Restylane Fynesse TM and Restylane Refyne TM have smaller gel particles for gentler support, targeting fine lines and wrinkles.

Reference Link: https://www.restylaneusa.com/

Teoxane is renowned worldwide for its innovative aesthetic products, backed by patented research technology. Teoxane has successfully registered its approval process with the FDA before releasing its products to the market. The full range of Teoxane includes unique fillers with varying gel densities, each tailored for specific areas of the face to achieve individualized results, from reducing fine lines and wrinkles to reshaping facial contours.

Why Teoxane is a Safe and Effective Filler:

• Produced with the highest quality standards and optimal safety in laboratories in Geneva.
• Contains 100% hyaluronic acid sourced from non-animal origin, biodegradable, and highly biocompatible, providing immediate results and long-lasting effects for many patients.

Official Teoxane Product Range:

• TEOSYAL RHA® 1: Treats small wrinkles on the face, neck, and chest.
• TEOSYAL RHA® 2: Targets moderate wrinkles on the upper face - forehead, frown lines, crow's feet, or enhances lip volume and contour.
• TEOSYAL RHA® 3: Addresses deep facial wrinkles such as nasolabial folds, vertical lip lines, deep wrinkles, and folds. Also fills cheeks and restores facial shape.
• TEOSYAL RHA® 4: Used for larger areas like the cheeks and overall facial contouring.
• TEOSYAL RHA® KISS: Enhances thin lips and creates well-defined lip contours.
• TEOSYAL® ULTRA DEEP: Fills deeper areas such as the cheekbones and chin.
• TEOSYAL® ULTIMATE: Adds volume to areas like the cheekbones, chin, jawline, and temples.

Reference Link: https://teoxane.vn/