The ratio of "good bacteria" and "bad bacteria" in the digestive system is typically kept balanced. When you take antibiotics to eliminate harmful bacteria causing infections, you also kill beneficial bacteria in your gut. The reduction of good bacteria allows harmful bacteria to thrive, leading to toxin production, inflammation, and diarrhea. Doctors may recommend probiotics like Acidophilus to counter this imbalance. If prescribed, it's important to know how to use Acidophilus correctly during antibiotic treatment.
Steps
Reduce the side effects of antibiotics

Consult with your doctor about the type and dosage of Acidophilus. Your doctor will prescribe the daily dose and the best form of Acidophilus for you. Dosages may vary, but people experiencing diarrhea due to antibiotics should take 10 - 20 billion CFU (colony-forming units per 1 ml) daily. Your doctor may recommend a higher or lower dose based on the antibiotic you're using, the duration of treatment, and your risk of developing colitis. Certain antibiotics, such as Cephalosporins, Fluoroquinolones, and Clindamycin, often cause diarrhea. Acidophilus comes in various forms, including capsules, tablets, and powder. Only use the form recommended by your doctor. Do not mix different forms (e.g., combining tablet and powder forms), as each contains different bacterial strains. Follow your doctor's advice regarding the duration of use, typically at least 1-3 weeks longer than the antibiotic treatment period.

Take Acidophilus and Antibiotics Separately. Taking Acidophilus and antibiotics at the same time will not be effective because probiotics promote the growth of good bacteria, while antibiotics destroy the beneficial bacteria in your body.
- You should take Acidophilus at least 1-2 hours before or after taking antibiotics. 2-4 hours is also a recommended timeframe.

Know How to Take Acidophilus to Maximize Its Effectiveness. Make sure that the Acidophilus is not expired and is stored correctly. Expired supplements or those not kept under recommended cold storage may lose their effectiveness. You should ensure regular consumption of Acidophilus. Occasionally, your doctor or the manufacturer may suggest taking Acidophilus with food or before breakfast when stomach pH levels are high.

Enhance Your Diet with Acidophilus-rich Foods. Yogurt is one of the foods rich in Acidophilus. Many yogurt brands on the market contain probiotics like Acidophilus. Some yogurt brands even advertise the specific probiotic strains inside their products.
- Consuming yogurt daily can help add more Acidophilus to your diet. However, you should reduce your yogurt intake if you are also using probiotic supplements.
Learn About Acidophilus and Its Benefits When Taken with Antibiotics

Understand Acidophilus. What is Acidophilus? Acidophilus (Lactobacillus acidophilus or L. acidophilus) is a "good bacteria" in the body. This beneficial bacteria helps break down food in the intestines and produces lactic acid to fight harmful bacteria. Acidophilus can naturally occur in the body, or you can supplement it through probiotic dietary supplements. Taking Acidophilus helps treat digestive disorders and many other conditions.
- Besides Acidophilus, there are many other available probiotics such as Lactobacillus strains. However, Lactobacillus acidophilus is the most commonly used probiotic.

Understand the benefits and mechanisms of Acidophilus with antibiotics. Clinical studies show that Acidophilus helps inhibit the growth of pathogens (disease-causing agents such as harmful bacteria) in the digestive system. Acidophilus is used to manage digestive disorders (e.g., irritable bowel syndrome), aid digestion, reduce vaginal yeast infections, treat other conditions like lung infections, skin diseases, and alleviate antibiotic-induced diarrhea.
- In the case of antibiotic-associated diarrhea, the antibiotic you take aims to destroy harmful bacteria but also kills the beneficial bacteria in your gut. A decrease in beneficial bacteria can lead to the overgrowth of harmful bacteria, producing toxins, causing inflammation, and diarrhea.

Understand the importance of preventing antibiotic-associated diarrhea. Most cases of diarrhea caused by antibiotics are mild and resolve after you stop taking the medication. However, antibiotic-related diarrhea can sometimes lead to serious issues such as colitis (ulcerative inflammation in the colon) or pseudomembranous colitis – a severe form of colon inflammation. About one-third of cases with long-term antibiotic use (usually in hospitals) may face a risk of Clostridium difficile infection, a severe and difficult-to-treat infection that causes frequent diarrhea.
- Recent important studies indicate that probiotics like Acidophilus can prevent or reduce antibiotic-associated diarrhea and effectively prevent Clostridium difficile infections.
- Clostridium difficile infections typically occur after taking antibiotics such as Fluoroquinolone, Cephalosporin, Clindamycin, and Penicillin.
Warning
- Discontinue all medications and consult your doctor if you experience swelling of the face or mouth – signs of an allergic reaction.
- Consult your doctor if you are pregnant, breastfeeding, immunocompromised, or have intestinal conditions before taking Acidophilus or antibiotics.
