Pigs are intriguing animals. While you may think their main purpose is to wallow in the mud before becoming bacon, these remarkable creatures actually play an essential role in advancing science. Researchers across various fields rely on them to deepen our understanding of numerous topics. Some experiments are innocent but fascinating, such as teaching AI to detect when a pig is stressed, while others are more controversial, involving organ transplants, gene editing, and cloning.
These little creatures have unlocked a vast range of knowledge, from insemination with coconut water to pioneering cross-species heart transplants. These represent some of the most captivating—and at times, ethically debated—ways pigs are utilized in cutting-edge scientific research.
10. Bionic Technology Reverses Erectile Dysfunction

It’s something we all face. As time passes, wear and tear take their toll, and eventually, things don’t function quite like they once did. Even pigs occasionally struggle with performance issues.
Now, a bionic patch has been introduced to resolve their limp struggles. In January 2023, Chinese researchers revealed a new technology designed to assist boars in maintaining their erections. This innovation is called artificial tunica albuginea (ATA). The device mimics the complex tissue structures of the penis and is strong enough to bear weight without damage. This enables the impaired members to become aroused again.
While there’s still a considerable distance before similar patches can be applied to humans, the researchers are optimistic that their breakthrough could contribute to male reproductive health in the future.
9. Synthetic Glue May Offer a Solution for Lactose Intolerance

Conditions like lactose intolerance, diabetes, and obesity can severely impact people's lives. Scientists from MIT propose that the solution could lie in a unique synthetic glue. This specialized adhesive adheres to the walls of the small intestine, where it regulates nutrient absorption. The gut plays a crucial role in nutrient uptake, but Giovanni Traverso and his team observed that it doesn’t always absorb as efficiently as it could. To address this, they created a chemical glue, inspired by how mussels attach to wet rocks by the sea.
But how does the glue make its way into the small intestine without sticking to other organs on the journey? This is where pigs come into play. The MIT team developed a drink containing the glue’s chemical ingredients, which only begin to combine when they encounter an enzyme in the small intestine. This reaction produces an adhesive compound known as polydopamine.
Experiments conducted on pigs showed that the glue could enhance the absorption of various nutrients, depending on its chemical makeup. Adding lactose led to a 20-fold improvement in lactose digestion compared to normal levels. Furthermore, incorporating a polydopamine lining with nanoparticles resulted in pigs absorbing less glucose. Researchers suggest this might have implications for treating diabetes and obesity, both conditions being linked to excessive glucose.
8. Genetically Modified Heart Transplants: A Revolutionary Medical Advancement or an Ethical Question?

In the summer of 2022, two brain-dead patients in New York were the recipients of genetically engineered pig hearts. Surgeons successfully carried out the complicated procedure, referred to as a xenotransplant, without any signs of organ rejection. Over a period of three days, the new hearts remained healthy, and neither patient showed signs of disease.
Scientists at New York University made ten modifications to the pig hearts. Six of these alterations involved adding human genes to promote healthy growth and reduce the risk of rejection, while the remaining four modifications focused on blocking certain pig DNA sequences.
This was not the first major achievement in pig heart transplants. Earlier, 57-year-old David Bennet underwent the first xenotransplant at the University of Maryland Medical Center. Bennet, who was battling terminal heart disease, sadly passed away two months after the procedure, possibly due to complications from the transplanted organ.
These experimental operations, though captivating, are fraught with ethical dilemmas. Critics worry that scientists could be crossing a line, playing God. Additionally, many animal rights groups strongly oppose this research due to its controversial nature.
However, some argue that the critical shortage of donor organs, particularly in the United States, cannot be ignored. Currently, there are 106,000 people on the transplant waiting list. On average, 17 people die each day while waiting for an organ. Scientists are hopeful that genetically modified pig transplants could alleviate some of this urgent problem.
7. Pigs Have the Ability to Breathe Through Their Anuses

Though it may sound absurd, this discovery could eventually be life-saving. Pigs are capable of absorbing oxygen through their rectums. This unexpected finding emerged when researchers sought an alternative to mechanical ventilators. When an ICU patient's oxygen levels drop, doctors typically rely on a ventilator, but this can sometimes harm the lung tissue.
Takanori Takebe has proposed a potential solution. The Japanese researcher has developed a method for the body to absorb oxygen through the intestines. His research involved flushing fluids into the rectums of pigs to study this phenomenon.
Takebe and his team began administering enemas to their pig subjects using a specialized oxygen-rich liquid known as perfluorocarbon. With each injection of the fluid, they observed a significant rise in the pigs' blood oxygen levels.
The researchers believe that this technique could potentially be applied to human patients, especially in regions where ventilators are scarce or unaffordable. Since perfluorocarbon is already utilized to support lung development in premature infants, the risk of harmful side effects is considered minimal.
6. Calcite Analysis Verifies the Oldest Known Animal Cave Painting

This discovery diverges from the previous entries in that it involves a cave painting rather than an actual pig. It is believed to be the oldest animal cave painting ever found. Archaeologists uncovered this ancient artwork in a remote cave on the Indonesian island of Sulawesi. The painting features a Sulawesi warty pig and measures approximately 5 inches (136 cm) by 21 inches (54 cm).
To determine the painting's age, scientists employed a uranium-based dating method. Maxime Aubert identified a calcite layer covering the pig image, which was found to be 45,500 years old. However, the painting itself may be even older, as Aubert noted, 'It could be much older because the dating we’re using only dates the calcite on top of it.'
Archaeologists have discovered two handprints near the back of a warty pig. From these prints, scientists aim to collect DNA samples that could offer valuable insights into the lives of early humans.
5. Pigs Trained to Play Video Games

In 2021, a study published in the Frontiers in Psychology journal described attempts to train pigs to play video games. The animals, including Hamlet and Omelette (two Yorkshire pigs) and Ebony and Ivory (Panepinto micro pigs), were coached at Purdue University to use their snouts to control a joystick.
The game they played was simple, but the pigs displayed impressive skill. Whenever they navigated toward a target using the controls, they were rewarded with a snack. Despite the absence of treats, they continued playing. Scientists praised the study, calling it 'remarkable,' and suggested that pigs possess a higher level of intelligence and cognitive abilities than previously believed.
"It is no small feat for an animal to grasp the concept that the behavior they are performing is having an effect elsewhere," wrote Dr. Candace Croney. "That pigs can do this to any degree should make us reconsider what else they are capable of learning and how such learning could affect them."
4. Headshots to Analyze Blood-Splatter Patterns

The use of animals for scientific testing often sparks ethical debates, particularly when it involves lethal experiments. In 2015, a study from New Zealand made waves for its disturbing focus on firing bullets through pig skulls to investigate blood spatter patterns.
While most of the pigs used in the study were sourced from butchers, five live adult pigs were shot as part of the experiment. The animals were sedated, bound to a table, and executed with a pistol or semi-automatic rifle. Three pigs were shot from a distance of 4 feet (1.2 meters), and the remaining two were shot at point-blank range.
Despite its ethical concerns, the Institute of Environmental Science and Research argues that the study provided valuable insights into 'gunshot-related back spatter,' with potential implications for solving gun crimes. When a bullet strikes the head, blood, tissue, and bone often spray outward in unpredictable ways, though not consistently. The study explored the reasons for this variability. Blood-splatter analysis allows forensic experts to discern between murder and suicide.
3. AI Robots Capable of Cloning Pigs

The combination of artificial intelligence and cloning represents two of the most debated realms in contemporary science. When these fields converge, they create a whirlwind of ethical dilemmas.
However, in June 2022, scientists introduced the first piglets cloned entirely by robots, without any human involvement. This groundbreaking work was carried out at the University of Nankai in Tianjin, China. The researchers believe that removing human participation in the cloning process significantly minimizes errors. The AI-driven machines reportedly outperform humans in successfully cloning pigs.
'Every step of the cloning procedure was automated, and no human hands were involved,' said researcher Liu Yaowei. 'Our AI-powered system can assess the strain within a cell and guide the robot to apply minimal force, reducing the cell damage that would typically result from human handling.'
2. A Novel Insemination Method Using Coconut Water

For many, coconut water is a refreshing, tropical drink enjoyed on warm days. But scientists in Uganda have discovered an unexpected new application for this beverage: artificial insemination in pigs.
Researchers at Gulu University are developing an unconventional technique that they hope could be adopted across African countries. The water from young coconuts is packed with beneficial nutrients such as sodium and potassium. The idea is to use this liquid to deliver semen into sows, increasing the likelihood of successful fertilization. Improving pig insemination is especially vital in Uganda, where the pork consumption rate is 7.5 pounds (3.4 kilograms) per capita annually. The team is optimistic that their findings will provide smallholder farmers with a cost-effective, accessible method to raise healthier pigs for meat production.
According to lead researcher Elly Ndyomugyenyi, 'The high levels of sodium and potassium in green coconuts are key factors that help improve sperm motility and longevity. These fruits are easily found in local markets, where they are sold alongside other common fruits.'
1. Facial recognition technology could enhance the quality of life for farm animals.

A groundbreaking scientific study is delving into the emotional well-being of farm animals. Researchers at the Pig Research Centre, part of Scotland’s Rural College (SRUC), believe their discoveries may improve the overall welfare of pigs.
In 2019, SRUC launched a project focused on using facial recognition to determine whether a pig is feeling content or distressed. The research team created both 3D and 2D images of pig faces, which are then analyzed at the University of the West of England. There, experts are exploring innovative ways to interpret a pig's emotional state based on its facial expressions.
While still under development, researchers suggest this technology could help spot health issues or welfare concerns on farms. 'Machine vision technology has the ability to offer an affordable, non-intrusive, and effective solution to biometrically track individual animals on farms,' said Melvyn Smith, an expert in the field.
'Our research has already achieved a 97% accuracy rate in identifying pig faces. Our next phase will be the pioneering use of machine vision to detect facial expressions related to emotions like happiness or distress in the pigs we've identified,' the team stated.
