
While the afterlife remains a mystery, the cause of death is often straightforward in modern times, thanks to scientific progress. However, this clarity fades as we delve into history, where many deaths are cloaked in mystery, sparking widespread speculation, rumors, and even contemporary conspiracy theories about their true nature. From explorers who vanished without a trace to leaders, artists, and innovators who succumbed to peculiar ailments, and individuals on the cusp of power who met untimely ends—these stories continue to intrigue and baffle us, leaving unanswered questions that persist through the ages.
1. Alexander the Great
Alexander the Great of Macedonia passed away on June 13, 323 BCE, following a two-week illness that left him so debilitated he lost the ability to speak. The sudden demise of the otherwise robust 32-year-old king was puzzling. Even more astonishing was the claim that his body showed no signs of decay for approximately six days after his death—a phenomenon his followers interpreted as evidence of his divine nature.
Contemporary theories about Alexander’s demise range from diseases like malaria and typhoid fever to West Nile encephalitis, possibly contracted from birds. As for the mystery of his seemingly preserved body, Katherine Hall, a senior lecturer at New Zealand’s University of Otago, proposes a chilling explanation: Alexander might not have been dead at all. Hall suggests he could have suffered from Guillain-Barré syndrome, an autoimmune condition causing paralysis, which would have left him immobile with slowed breathing and a lowered body temperature. If Hall’s theory holds, Alexander’s embalmers might have unintentionally ended his life, though he was likely in a deep coma by then, unaware of their actions. —Ellen Gutoskey
2. Grigori Rasputin
Grigori Rasputin. | Laski Diffusion/Getty Images Rasputin), Justin Dodd/Mytour (background)Whether seen as a mystic or a fraud, Grigori Rasputin managed to earn the trust of the Russian royal family, but his swift ascent to influence made him many deadly foes. His assassination in 1916 has become the stuff of legend, even inspiring a 1978 disco hit by Boney M., due to the extraordinary measures required to end his life. Poisoned with cyanide-laced cakes and wine, shot multiple times, and still surviving, his killers ultimately bound his wrists and threw him into the Neva River. His body was later discovered beneath the ice, with evidence suggesting he had freed himself from his restraints before finally drowning.
The tale of Rasputin’s supernatural resistance to death is largely a fabrication. Prince Felix Yusupov, one of the aristocrats involved in the Mad Monk’s assassination, embellished the events to enhance his own standing by portraying Rasputin as an otherworldly being. The autopsy findings, however, reveal a simpler truth: Rasputin died from a gunshot wound to the head, not from poisoning or drowning. —Lorna Wallace
3. Edgar Allan Poe
Edgar Allan Poe. | © CORBIS/Corbis via Getty Images (Poe), Justin Dodd/Mytour (background)Edgar Allan Poe, the master of macabre tales like “The Tell-Tale Heart” and “The Raven,” left behind one final enigma. On October 3, 1849, the 40-year-old writer was discovered in Baltimore, disoriented and gravely ill. Suffering from delirium, he couldn’t explain his condition or account for his whereabouts during the preceding six days. Poe had been in Richmond, Virginia, and was en route to Philadelphia, but he never reached his destination.
When Poe was found, he was dressed in unfamiliar clothing; his health continued to decline, and he passed away on October 7. The doctor attending him attributed his death to phrenitis, or brain congestion, a term occasionally used to mask the effects of heavy drinking.
Since then, historians have debated various theories about Poe’s demise, ranging from common causes like alcoholism, tuberculosis, or a physical attack to more dramatic possibilities. Some suggest he was coerced into participating in a voting fraud scheme called “cooping,” prevalent in Baltimore at the time, where victims were intoxicated and forced to vote multiple times. Others speculate he contracted rabies from an infected cat. The disappearance of Poe’s medical records only deepened the mystery.
Poe was unable to explain his condition, uttering only one word: Reynolds. The identity of this reference and its connection to his death remain unsolved. —Jake Rossen
4. Agnès Sorel
Agnès Sorel. | Hulton Archive/Getty Images (Sorel), Justin Dodd/Mytour (background)Agnès Sorel is renowned for three key aspects: her role as the officially recognized mistress of King Charles VII of France, the myth of her wearing dresses that exposed her preferred breast (a misconception likely arising from a posthumous portrait depicting her as the Virgin Mary nursing baby Jesus), and her enigmatic death in 1450 while expecting her fourth child.
Initially, Sorel’s death was blamed on dysentery, but suspicions of poisoning arose. In 2005, paleopathologist Philippe Charlier confirmed these suspicions by analyzing her remains and discovering lethal mercury levels. This suggests she was likely murdered, with the prime suspect being the Dauphin (later Louis XI), who opposed his father and may have sought to eliminate his influential mistress. However, the possibility remains that she consumed the mercury voluntarily, as it was a common ingredient in both medicines and cosmetics at the time. —LW
5. Abby and Andrew Borden
On June 20, 1893, a jury acquitted Lizzie Borden of using an ax to murder her father, Andrew, and stepmother, Abby, in their Fall River, Massachusetts, home on August 4, 1892. If Lizzie didn’t commit the crime, the question remains: who did?
Russell Aiuto notes in Crime Library that numerous accusations were made regarding the potential murderer, including Lizzie's uncle, John Morse, who was visiting the Bordens during the killings; the family’s maid, Bridget Sullivan; and their neighbor, Dr. Seabury Warren Bowen. Aiuto also mentions other suspects, such as “a madman in a straw hat” and “one of Lizzie's Chinese Sunday School students.” More recent theories suggest Lizzie’s sister, Emma, as the culprit, despite her alibi of being 15 miles away on vacation. Another unusual theory involves Andrew’s alleged illegitimate son, William. (While a William Borden did live in Fall River, his connection to Andrew remains unclear.)
Initially, police arrested a Portuguese immigrant, but inconsistencies in Lizzie’s story, her lack of emotional response to the murders, and other peculiarities shifted suspicion to her. After her acquittal, many believed Lizzie was guilty and had escaped justice. She maintained her innocence until her death in 1927 but lived as an outcast in Fall River. The case remains unsolved, and the true killer may never be known. —Erin McCarthy
6. Meriwether Lewis
Meriwether Lewis. | Heritage Art/Heritage Images via Getty Images (Lewis), Justin Dodd/Mytour (background)Between May 1804 and September 1806, Meriwether Lewis and William Clark spearheaded the Corps of Discovery expedition, journeying from St. Louis, Missouri, to the Pacific Ocean and back. Covering over 8000 miles, they amassed invaluable knowledge about the Louisiana Purchase and the American West, losing only one team member—a remarkable achievement. This makes Lewis’s mysterious death at a Tennessee tavern in 1809 even more perplexing.
In September 1809, after his tenure as governor of the Upper Louisiana Territory, Lewis embarked on a trip to Washington, D.C. While traveling down the Mississippi River, he contracted malaria. His companion, James Neelly, noted that Lewis appeared mentally unstable. Neelly, Lewis, and two servants left the river near present-day Memphis and ventured onto the Natchez Trace. On October 10, Lewis and the servants arrived at Grinder’s Stand, a small inn run by Priscilla and Robert Grinder. Lewis’s erratic behavior alarmed Mrs. Grinder, who allowed him to stay in a separate cabin while she, her children, and a maid slept in another. The servants stayed in a barn 200 yards away.
According to Neelly’s account of Mrs. Grinder’s testimony, she heard two gunshots around 3 a.m. and the sound of something heavy hitting the floor. Peering through her window on a moonless night, she allegedly saw Lewis crawling and pleading for water. Too frightened to intervene, she waited until morning to enter his cabin, where she discovered him fatally wounded.
Some historians argue that Lewis, depressed due to his illness and struggles as governor, committed suicide. Others speculate that Mrs. Grinder, the sole adult witness to his final moments, may have killed him for undisclosed reasons. Locals theorized that Robert Grinder returned home to find Lewis with his wife and shot him, prompting her to fabricate the story. Additional theories include political assassination or murder by an unknown assailant. The truth remains elusive. —Kat Long
7. Amelia Earhart
In 1937, renowned pilot Amelia Earhart, accompanied by navigator Fred Noonan, set out to fly around the world. On July 2, nearing the end of their journey, they departed from New Guinea bound for Howland Island but vanished before reaching their destination. The most widely accepted theory is that their plane ran out of fuel and plunged into the Pacific Ocean, resulting in the deaths of both Earhart and Noonan.
An extensive search was launched, but neither the aircraft nor its occupants were ever recovered (though recent sonar scans have identified an object resembling a plane in the suspected crash area). The mystery surrounding their disappearance has fueled numerous theories about their ultimate fate.
One hypothesis suggests Earhart and Noonan ended up on Nikumaroro (also known as Gardner Island), approximately 350 miles southeast of Howland, where they perished as castaways—possibly falling victim to coconut crabs. However, the identity of the skeletal remains found there remains disputed. Another theory claims Earhart was a spy captured by the Japanese, later returning to the U.S. under a new identity. Yet another posits that both died in Japanese custody. None of these theories have been definitively proven. —LW
8. The Somerton Man
In 1948, a man was discovered dead under the esplanade on Australia’s Somerton Beach. He was dressed in a full suit with all labels removed, and carried no identification, though he had bus and train tickets. Authorities linked him to an abandoned suitcase but failed to identify him. A torn piece of paper with the phrase tamám shud (“it is ended” in Persian) was later found in his pocket, deepening the mystery.
Every effort to identify the Somerton Man ended in failure. Despite his distinctive physical traits, no one came forward to recognize him or claim his body. An autopsy showed significant internal bleeding and an enlarged spleen, leading the coroner to suspect poisoning. However, no motive for his potential murder was ever uncovered.
Police eventually traced the book they believed the torn paper in the Somerton Man’s pocket came from. Inside, they found a phone number linked to a nurse named Jessica Thomson. (The book also contained an indecipherable code that remains unsolved.) Thomson claimed to have given a copy of the book to a man who was still alive and in possession of his copy. She denied knowing the Somerton Man, though she reportedly fainted upon seeing a cast of his face. Intriguingly, her son shared the same rare dental and ear features as the Somerton Man, whose body was discovered near her residence.
In 2022, Australian professor Derek Abbott analyzed DNA from hair found in the Somerton Man’s death mask, proposing he was Carl Webb, a man with no genetic link to Thomson’s son. However, the Australian government has not officially confirmed this identification, leaving the case unresolved. —Kerry Wolfe
9. Christopher Marlowe
Christopher Marlowe. | Keystone/Getty Images (Marlowe), Justin Dodd/Mytour (background)On May 30, 1593, Elizabethan playwright Christopher Marlowe, aged just 29, was fatally stabbed by his associate, Ingram Frizer. According to the official account, the two quarreled over who should settle the tavern bill, leading to a violent altercation. (Technically, the incident occurred at the home of Dame Eleanor Bull, not a tavern.)
Many find this explanation too simplistic. At the time, Marlowe was awaiting trial for atheism, a capital offense. Additionally, some historians believe he served as a spy for Queen Elizabeth’s government. It’s also suspicious that Frizer was pardoned for the murder, claiming self-defense.
If Marlowe’s death wasn’t the result of a mundane fight, what truly happened? One theory suggests Marlowe possessed evidence implicating members of Queen Elizabeth’s Privy Council in atheism, leading to his assassination to silence him. In an era rife with espionage and betrayal, it’s also possible the killing was ordered by one of Marlowe’s enemies. Another theory posits that his death was staged to save him from execution for atheism, fueling the conspiracy that he continued writing plays under the name William Shakespeare. —EG
10. Zachary Taylor
Zachary Taylor. | Hulton Archive/Getty Images (Taylor), Justin Dodd/Mytour (background)Shortly after a Fourth of July celebration in 1850, President Zachary Taylor’s health took a sudden turn for the worse. He experienced severe cramps, diarrhea, and unquenchable thirst, exacerbated by the sweltering summer heat. After four days of suffering, the 12th president died from gastroenteritis, having served only 16 months in office.
Taylor’s sudden death has sparked various theories. Some historians attribute his fatal stomach issues to spoiled cherries and iced milk, while others suspect arsenic poisoning by pro-slavery Southerners. When his body was exhumed in the 1990s, no significant traces of arsenic were found, debunking the poisoning theory. Recent studies suggest contaminated drinking water at the White House may have been the culprit. In the 1840s, Washington, D.C. lacked modern sewage systems, and the White House water supply came from a spring near a sewage dump. This contaminated water may also have contributed to the deaths of two other presidents from the 1840s: William Henry Harrison and James K. Polk, both of whom suffered from gastroenteritis before dying of pneumonia and cholera, respectively. —Michele Debczak
11. The Princes in the Tower
Edward V and Richard, the Princes in the Tower. | Hulton Archive/Getty Images (princes), Justin Dodd/Mytour (background)Richard III is often portrayed as a villain, a reputation further tarnished by his suspected role in the disappearance of his nephews: 12-year-old Edward V and his younger brother Richard, collectively known as the “Princes in the Tower.” Following his father’s death in 1483, Edward V, too young to rule, was placed under the guardianship of the Duke of Gloucester. Amid the chaos of the War of the Roses, the duke sent the boys to the Tower of London, ostensibly for their protection (it was also customary for heirs to stay there before coronation). However, Parliament later declared both Edward V and his brother illegitimate, and the duke was crowned King Richard III.
The boys were last spotted playing in the tower’s garden on June 16, 1483. Sometime afterward, it is believed they were likely murdered. In 1674, workers renovating the tower unearthed a chest containing the skeletons of two children, presumed to be the princes, though the remains have never undergone DNA testing. While Richard III is the primary suspect, others, such as his ally Henry Stafford or Henry VII, may have also had motives to eliminate potential rivals to the throne.
There’s also speculation that the boys weren’t killed at all. Philippa Langley, who discovered Richard III’s remains under a parking lot, theorizes that they survived and later attempted, unsuccessfully, to reclaim the throne under the names Lambert Simnel and Perkin Warbeck. However, this theory lacks definitive evidence. —LW
12. Natalie Wood
Natalie Wood. | Hulton Archive/Getty Images (Wood), Justin Dodd/Mytour (Getty Images)The death of actress Natalie Wood feels like a plot from a Hollywood thriller rather than real life. Yet the Splendor in the Grass star tragically drowned around midnight on November 28–29, 1981, raising persistent questions about how Wood, who had a fear of water, ended up in the ocean.
Theories about what happened that night begin with Wood’s activities leading up to it. She, her husband Robert Wagner, and actor Christopher Walken (her co-star in the film Brainstorm) were aboard their yacht, Splendour, along with the yacht’s skipper, Dennis Davern. The night before her death, the group had dinner and drinks at a restaurant, returning to the yacht visibly intoxicated. Wood reportedly went to bed first, while Walken and Wagner stayed up. When Wagner checked their cabin, he found Wood missing, along with the yacht’s inflatable dinghy. Wagner was believed to be the last person to see her alive.
The next morning, Wood was found floating in the water about a mile from the yacht, dressed in a flannel nightgown, down jacket, and wool socks. The dinghy was discovered nearby at Blue Cavern Point, with the key in the ignition turned off and the oars still secured. Although her death was initially ruled an accidental drowning in 1981, the coroner noted multiple bruises on her arms and legs and an abrasion on her left cheek, believed to have occurred when she attempted to board the dinghy from the yacht and fell into the water. Toxicology reports indicated a blood alcohol content of 0.14 percent, suggesting she may have fallen overboard while intoxicated.
In 2011, the Los Angeles County Sheriff’s Department reopened the case after receiving new information from unnamed sources. Two years later, the coroner revised Wood’s cause of death to “drowning and other undetermined factors,” citing unexplained injuries such as a scratch on her neck, an abrasion on her forehead, and bruises on her arms and knee, which could not rule out non-accidental causes.
Dennis Davern, the yacht’s captain, admitted in a 2011 interview that he had lied during the initial investigation. He claimed Wood and Wagner had a heated argument that night, allegedly over Walken, and that Wagner instructed him to withhold this information. Davern later accused Wagner, who was named a “person of interest” in 2018, of being responsible for Wood’s death. Wagner, however, denies any involvement, stating in his memoir Pieces of my Heart that he last saw Wood when she went to bed after he and Walken argued. In 2022, detectives confirmed all leads had been exhausted, but the case remains open. —Shayna Murphy
13. Roopkund Lake Skeletons
Roopkund Lake, nestled in a remote Himalayan valley, hides a grim secret: hundreds of human skeletons scattered in and around its waters. Early theories suggested the bones belonged to soldiers or traders, but no weapons were found, and the lake is not on a trade route. However, it lies on a Hindu pilgrimage path. Forensic analysis in 2004 revealed skull injuries, leading to the theory that the skeletons are the remains of 9th-century pilgrims killed by massive hailstones.
While the hailstone theory seemed plausible, a 2019 study complicated the narrative. DNA analysis of 38 skeletons revealed that the lake contained remains from at least three distinct groups. One group, of South Asian origin, dated between the 7th and 10th centuries, while another group, of eastern Mediterranean descent, and one individual of southeast Asian ancestry, dated between the 17th and 20th centuries.
The presence of skeletons from different ancestries and time periods in the same lake remains a mystery. Unfortunately, frequent disturbances by trekkers in the area may hinder efforts to uncover the truth. —LW
14. Vincent van Gogh
Self-portrait of Vincent van Gogh. | VCG Wilson/Corbis via Getty Images (van Gogh), Justin Dodd/Mytour (background)The life of Dutch Post-Impressionist painter Vincent van Gogh (1853-1890) is as famous as his art, often overshadowed by his personal struggles. In 1888, van Gogh famously severed his own ear, likely due to an undiagnosed mental health issue. On July 27, 1890, after painting in a wheat field over a mile away, he returned to his inn in Auvers-sur-Oise, France, with a gunshot wound to his torso. He succumbed to his injuries two days later.
Many believe van Gogh’s fatal wound was self-inflicted. His doctor, Paul Gachet, informed van Gogh’s brother that the artist had “wounded himself.” Van Gogh, who had previously attempted suicide by poisoning, also claimed to have shot himself.
However, some dispute this narrative. In 2011, authors Steven Naifeh and Gregory White Smith (Van Gogh: The Life) proposed that a 16-year-old boy, René Secretan, accidentally shot van Gogh. According to this theory, van Gogh took the blame to protect the teenager from legal consequences. The gun was never found.
This theory faced criticism, but doubts about van Gogh’s death persist. A 2020 paper in the American Journal of Forensic Medicine and Pathology, co-authored by pathologist Michael Baden, argued that van Gogh likely couldn’t have shot himself without sustaining a powder burn. Leo Jansen, a van Gogh exhibit curator, acknowledged that while there’s no definitive proof of suicide, the artist’s own account has been the basis for the prevailing narrative. —JR
15. Hinterkaifeck Killings
In late March 1922, Andreas Gruber observed peculiar occurrences around his Bavarian farm: an unfamiliar newspaper, mysterious footprints in the snow leading from the forest, and a missing key. He dismissed these oddities, much like he had months earlier when the maid quit after hearing eerie noises in the attic, which she believed were caused by a ghost.
On March 31, a new maid, Maria Baumgartner, arrived. After that, the farm fell silent. On April 4, concerned neighbors investigated and discovered the bodies of Maria and the entire Gruber family—Andreas, his wife Cäzilia, their daughter Viktoria, and Viktoria’s children, Cäzilia and Josef. All had been brutally killed by blows to the head with a mattock. The killer(s) remained in the house for days, cooking and tending to the farm.
Investigators explored several suspects, including Lorenz Schlittenbauer, who had been romantically involved with Viktoria before her father ended the relationship. Schlittenbauer not only had ties to the family but was also part of the initial search party and showed no hesitation in handling the bodies.
Despite extensive efforts, police found no conclusive evidence to link anyone to the murders. The farm was demolished the following year. In a desperate attempt to solve the case, the victims’ heads were sent to a clairvoyant in Munich, but this yielded no results. In 2007, the Fürstenfeldbruck Police Academy revisited the case and reached a consensus on the likely perpetrator, though the theory remains undisclosed to protect the suspect’s living relatives. —LW
16. Sir John Franklin
Sir John Franklin. | Hulton Archive/Getty Images (Franklin), Justin Dodd/Mytour (background)The exact date of Arctic explorer Sir John Franklin’s death is known: June 11, 1847. However, the circumstances surrounding his demise remain an unsolved mystery.
Franklin, along with a crew of over 100 men aboard two well-equipped ships, set sail from England in May 1845 to discover the Northwest Passage. The British public anticipated a triumphant return within three years, but it wasn’t until 1859—14 years later—that a note found in a stone cairn revealed the fate of the expedition.
Franklin guided the expedition into Lancaster Sound, the largest passage through Arctic Canada, and spent the winter on a small island. The following summer, they traveled south along King William Island’s western edge, a triangular landmass surrounded by icy waters. The ships became trapped in ice in September 1846 and remained immobilized through the winter, spring, and early summer of 1847. Despite this, the crew remained healthy, and the mission seemed on track.
A cascade of tragedies followed. Franklin died in June under unknown circumstances, and his body was never recovered. Nine officers and 15 sailors also perished, their causes of death equally mysterious. The ships remained trapped in ice, forcing the crew to endure another harsh winter. On April 22, 1848, they abandoned the vessels and attempted to march to mainland North America, ultimately meeting their demise.
The fragmented details of Franklin’s and the expedition’s fate were reconstructed through extensive searches of the Northwest Passage between 1847 and 1859. Evidence from campsites, debris, skeletal remains, and a rust-stained note provided some insight. Despite ongoing discoveries of artifacts and clues by modern archaeologists, no definitive explanation—whether from a body, grave, journal, ship’s log, or oral history—has emerged to clarify the circumstances of Sir John Franklin’s death. —KL
17. John F. Kennedy
John F. Kennedy. | National Archive/Newsmakers/Getty Images (Kennedy), Justin Dodd/Mytour (background)For some, the events surrounding U.S. President John F. Kennedy’s death are clear: On November 22, 1963, while riding in a motorcade through Dallas, Texas, he was fatally shot by Lee Harvey Oswald. However, for many—including 65 percent of Americans, according to a 2023 Gallup poll—the assassination is riddled with inconsistencies that suggest a conspiracy.
The infamous footage of the shooting, captured by Abraham Zapruder, has sparked theories of a second shooter. Critics highlight Kennedy’s head jerking backward (implying a shot from the front, contrary to the Warren Commission’s findings) and the improbability of Oswald reloading and re-aiming in the short time between shots. Suspicion also surrounds the “umbrella man” on the sidelines and the so-called “magic-bullet theory,” which describes the bullet’s path through Kennedy and into Texas Governor John Connally. Additionally, some eyewitnesses reported hearing shots from the grassy knoll.
These theories have been met with counterarguments. For example, determining the source of gunshots by sound is unreliable. The “umbrella man” was later identified as Louie Steven Witt, who admitted to taunting the president with the umbrella, a symbolic jab at British Prime Minister Neville Chamberlain, whom Kennedy’s father had supported.
As for who orchestrated the assassination, theories abound. Suspects include Vice President Lyndon B. Johnson, Fidel Castro, and the CIA—a theory endorsed by JFK’s nephew, Robert Kennedy Jr. Actor Rob Reiner and journalist Soledad O’Brien recently explored these possibilities in their podcast, Who Killed JFK?, released on the 60th anniversary of the assassination. —LW
18. Charles Francis Hall
Charles Francis Hall, a Cincinnati newspaper publisher, was an improbable polar explorer. Despite lacking navigational expertise or survival training, he led two lengthy expeditions to the Canadian Arctic to uncover the fate of the Franklin expedition. In 1871, Hall embarked on a mission to reach the North Pole.
With $50,000 in government funding, Hall secured his own ship, the Polaris, and assembled a scientific team and crew. However, tensions quickly arose between the German and American crew members, as well as between the ship’s captain and assistant captain. Conflicts escalated, particularly between Hall and Dr. Emil Bessels, the German physician and zoologist. By the time they settled in a Greenland harbor for the winter, the situation was nearing a breaking point.
In late October, after returning from a scouting trip, Hall drank coffee and fell severely ill, experiencing delirium, hallucinations, and partial paralysis. He accused crew members of poisoning him and refused food or drink unless provided by Second Mate William Morton or his Inuit guide, Taqulittuq. Hall’s condition briefly improved, but after allowing Bessels to resume treatment, he slipped into a coma and died on November 8, 1871.
A naval inquiry ruled Hall’s death as natural, but suspicions of foul play persisted, with Bessels and other crew members under scrutiny. In 1968, historian Chauncey C. Loomis exhumed Hall’s body and found high levels of arsenic in his hair and nails, suggesting poisoning.
However, arsenic was a common medical treatment at the time, and Bessels likely carried it in his supplies. It’s possible Hall or Bessels accidentally administered a lethal dose. Loomis couldn’t conclusively prove murder, leaving the case unresolved. —KL
19. Wolfgang Amadeus Mozart
Wolfgang Amadeus Mozart. | Hulton Archive/Getty Images (Mozart), Justin Dodd/Mytour (background)In the autumn of 1791, the celebrated composer Wolfgang Amadeus Mozart fell ill and confided to his wife, “I am certain I have been poisoned. I can’t shake this thought.” He briefly recovered but dismissed his fears. By November 20, however, he was bedridden with fever, rash, swelling, and vomiting, and on December 5, he passed away.
The parish register listed his cause of death as “severe miliary fever,” a nonspecific term referring to a rash, leaving room for speculation. Rumors of poisoning, possibly by composer Antonio Salieri, emerged but lacked evidence. Over time, numerous theories have been proposed, including strep infection, subdural hematoma, kidney disease, trichinosis from undercooked pork, and vitamin D deficiency, though none have been conclusively proven. —LW
20. The Paste Eater
A peculiar headstone in Goldfield, Nevada’s Pioneer Cemetery bears the epitaph, written in red paint, “UNKNOWN MAN DIED EATING LIBRARY PASTE. JULY 1908.” Local legend claims it marks the grave of a homeless man who, while searching a library’s trash for food, consumed a jar of book paste—a mixture of flour, water, and alum—leading to his death. The man’s identity remains unknown, and some believe the story is a hoax, while others insist it’s true. —KW
21. The Hikers at Dyatlov Pass
In 1959, nine Russian hikers were discovered dead after camping in the northern Ural Mountains. Their injuries raised numerous questions: How did their broken bodies end up far from their tent? Why did some have orange-tinted skin, and why were eyes and a tongue missing?
A 2021 study aimed to solve the mystery of the Dyatlov Pass incident. The official explanation points to a “compelling natural force,” with researchers using CGI to simulate a slab avalanche that could have caused the hikers’ injuries without killing them instantly. This would explain why they fled the camp before succumbing to their wounds. Scavengers may have removed their eyes and tongue, and exposure to the elements could have caused partial mummification. Despite this, many still attribute the deaths to supernatural causes or government conspiracies. The incident inspired True Detective: Night Country. —MD
22. Tycho Brahe
Tycho Brahe. | Apic/Getty Images (Brahe), Justin Dodd/Mytour (background)Danish astronomer Tycho Brahe led an eccentric life (he owned a pet elk and wore a metal nose after losing his in a duel over a math dispute!) and met a mysterious end. In 1601, Brahe attended a banquet and refused to relieve himself due to social etiquette. By the time he finally used a toilet, he was in severe pain and unable to urinate. He died 11 agonizing days later.
After his death, rumors of poisoning circulated, though the official cause was a burst bladder. In the 1990s, tests on his exhumed hair revealed high mercury levels. Whether Brahe ingested mercury medicinally or was poisoned remains unclear. Some suspect his assistant, Johannes Kepler, who was frustrated by Brahe’s reluctance to share his astronomical discoveries. —JR
In 2010, Brahe’s body was exhumed again, and further analysis revealed that the mercury levels in his system were not lethal. Theories about his death shifted back to urinary tract issues, though the exact cause remains unclear—it could have been a burst bladder, uremia from an enlarged prostate, or another urinary complication. —LW
23. Karen Silkwood
Karen Silkwood. | Mark Peterson/Corbis via Getty Images (Silkwood), Justin Dodd/Mytour (background)On November 13, 1974, Karen Silkwood, a plutonium lab technician and whistleblower, died in a single-car accident. Her Honda Civic veered off Oklahoma’s State Highway 74 and crashed into a concrete abutment, causing fatal injuries. An autopsy revealed alcohol and Quaaludes in her system, leading investigators to conclude she fell asleep at the wheel.
From the start, there were indications of foul play. The 28-year-old activist was en route to Oklahoma City to meet a New York Times reporter and a union representative when the crash happened. She reportedly carried a manila folder containing photos and documents exposing safety violations at her workplace. The folder, which Silkwood believed would reveal Kerr-McGee Corporation’s negligence at the Cimarron River nuclear facility, was never found.
After her death, union officials hired an auto accident specialist to investigate. He found evidence, including skid marks and a dent in her car’s rear bumper, suggesting another vehicle had forced her off the road. Although the FBI investigated, they agreed with the medical examiner’s conclusion that Silkwood’s death resulted from alcohol and Quaalude use.
Her autopsy also revealed dangerous levels of plutonium in her lungs and digestive tract, indicating she had ingested it. Her apartment was contaminated too, with traces of plutonium in the kitchen, bathroom, and even a sandwich in her fridge.
Silkwood’s plutonium exposure wasn’t entirely unexpected. On November 5, an alpha detector alerted her to contamination. Traces were found on her gloves, though no holes were detected, and no significant contamination was found in her work area. Kerr-McGee conducted decontamination and monitored her for five days, during which high levels of plutonium were consistently detected. By November 12, she was exhaling contaminated air.
While Kerr-McGee claimed Silkwood contaminated herself intentionally, her supporters believed she was targeted to silence her. Her death inspired nuclear safety activists, and she became a symbol of worker-safety rights. The Cimarron River plant closed in 1976. Though no one was charged in her death, her estate sued Kerr-McGee and won a $1.38 million settlement in 1986. —SM
24. Elisa Lam
The Cecil Hotel in Los Angeles has a notorious history, including multiple deaths and being a temporary residence for the Night Stalker, Richard Ramirez, during his killing spree. The most infamous death is that of 21-year-old Elisa Lam, who was last seen alive at the Cecil on January 31, 2013.
Two weeks after her disappearance, police released elevator footage showing Lam behaving erratically—pressing multiple buttons, making strange gestures, and peering into the hallway before hiding. Her body was discovered on February 19 in a rooftop water tank after guests reported low water pressure and discolored, odd-tasting water.
An autopsy concluded Lam’s death was an accidental drowning, with no signs of foul play or suicide. Toxicology reports suggested she may have stopped taking her bipolar medication, potentially triggering a psychotic episode that could explain her behavior and contribute to her death. However, questions linger about how she accessed the locked roof and entered the tall water tank, with some speculating supernatural involvement. —LW
25. Amy Robsart
On September 8, 1560, the staff of Cumnor Place returned from a day at the fair to find Amy Robsart, the lady of the house, dead at the bottom of a short staircase. The 28-year-old wife of Robert Dudley, 1st Earl of Leicester, had been alone in the home while her husband was at court. Her neck was broken, and she had two deep head wounds, but no other injuries.
Questions and conspiracy theories arose immediately: Did she trip and fall, or did she intentionally throw herself down the stairs? Or was she murdered on Dudley’s orders, as he was a favorite—and rumored lover—of Queen Elizabeth I?
Rumors of Dudley poisoning his wife had circulated since late 1559. The Spanish ambassador, Álvaro de la Quadra, allegedly heard Dudley boast in March 1560 that he would be in a “new position” by year’s end. In Death and the Virgin: Elizabeth, Dudley and the Mysterious Fate of Amy Robsart, Chris Skidmore writes that de la Quadra believed Dudley and Elizabeth had a pact to marry after Amy’s death.
Testimony from a servant suggested Robsart, who insisted her staff attend the fair and grew angry when some wanted to stay, may have been suicidal. She was also said to suffer from an illness in one breast, which kept her from court. However, William Cecil, the queen’s private secretary, claimed Dudley spread this rumor. De la Quadra wrote that Cecil told him they planned to kill Robsart while claiming she was ill. Robsart’s death was announced the day after de la Quadra’s letter, and Dudley, aware of the suspicion, wrote, “I have no way to purge myself of the malicious talk I know the wicked world will use.”
The coroner’s inquest ruled Robsart’s death an accidental fall, but rumors persisted, damaging Dudley’s relationship with Queen Elizabeth, as she could not marry someone embroiled in such scandal.
Despite the passage of centuries, speculation about Amy Robsart’s death continues. In 1956, surgeon Ian Aird proposed that Robsart might have suffered from breast cancer that spread to her spine, weakening her bones to the point where even a minor fall could have caused a fracture. In The Life of Elizabeth I, Alison Weir suggests William Cecil may have orchestrated Robsart’s death: “He foresaw that if she died under suspicious circumstances, suspicion would inevitably fall on her husband … Cecil also knew Elizabeth, conservative by nature, would hesitate to risk her reputation and throne by marrying a man with such a tarnished image.” Cecil reportedly regained favor swiftly after Robsart’s death and Dudley’s exile from court.
Modern historians have also pointed to Sir Richard Verney, a Dudley supporter suspected in the 1560s, as a potential culprit. In Monarchy and Matrimony: The Courtships of Elizabeth I, Susan Doran notes, “Most historians have concluded Dudley was innocent … or at least found the evidence against him unconvincing and improbable.” The mystery of Robsart’s death remains unresolved. —EMC
