
The FDA has authorized the first app to treat major depressive disorder, a condition affecting an estimated 21% of U.S. adults during their lifetime. This app, Rejoyn, is designed to complement traditional treatment for major depressive disorder. In a clinical trial involving 386 adults with the condition, who were also taking antidepressants, those who used the app saw significant improvements in depression symptoms after six weeks.
Using digital tools to enhance mental health is nothing new. Numerous apps already exist for activities like meditation, journaling, and even connecting with therapists. The FDA has also approved apps for conditions such as ADHD, substance use disorder, and insomnia.
Rejoyn is expected to be available by prescription for both iOS and Android devices in the summer of 2024. However, there is currently no information on the app’s price or whether insurance providers will cover it. Here's what we know about how Rejoyn works and whether it’s worth considering once it becomes available.
What to Expect from Rejoyn
Rejoyn offers a six-week program featuring cognitive behavioral therapy (CBT) lessons, exercises, and personalized reminders. Throughout the program, you will engage in three lessons and three exercises each week. For an additional four weeks after the program, you can continue to access the lessons for review. Each lesson (a brief video followed by an activity) takes 3-4 minutes, while exercises range from 11-26 minutes in duration.
As stated by Otsuka, the company behind Rejoyn, the lessons focus on cognitive restructuring (identifying and reframing negative thought patterns), behavioral activation (intentionally increasing goal-oriented behaviors, physical activity, and social engagement), and emotional regulation (the ability to manage or control emotional responses and the intensity of those emotions).
Who is Rejoyn Ideal For?
Rejoyn is designed for individuals aged 22 and older who have been diagnosed with depression. It’s particularly well-suited for those who are comfortable with technology and wish to use digital tools alongside traditional therapy and medication for managing depression.
Dr. Sanam Hafeez, neuropsychologist and director of Comprehend the Mind, stated, "While Rejoyn is a groundbreaking development as the first prescription digital treatment for major depressive disorder, its effectiveness and suitability may differ from person to person. It's vital to consult with a therapist to determine if Rejoyn is the right option and to create a personalized treatment plan that meets individual needs."
How Can You Access Rejoyn?
Rejoyn requires a prescription. You’ll need to consult with your primary care physician, psychiatrist, or psychologist to discuss your depression symptoms and potential treatment options.
According to Hafeez, "During the consultation, the healthcare provider will assess the individual's symptoms, medical history, and ongoing treatments. They will then discuss treatment choices, including Rejoyn, in conjunction with traditional therapies such as medication and psychotherapy. If Rejoyn is found to be appropriate, the provider will prescribe the app."
Hafeez added, "While Rejoyn offers tools to help manage symptoms, it may not directly address the root causes of depression in the same way therapy and medication do. Nevertheless, it could serve as a helpful support between therapy sessions."
Other Apps That May Help With Depression
Hafeez mentioned that there are non-prescription apps showing promise in alleviating symptoms of depression. She highlighted the following examples:
Headspace provides guided mindfulness and meditation exercises that aim to reduce stress and enhance emotional well-being. Hafeez stated, "Research suggests that mindfulness-based techniques can effectively reduce symptoms of depression and anxiety."
Woebot is a chatbot-based app that uses CBT techniques through conversational interactions. Hafeez noted, "Studies have shown that Woebot can effectively reduce symptoms of depression and anxiety, especially among younger users."
Happify offers activities and games designed to enhance happiness and well-being by addressing negative thoughts and behaviors. Hafeez mentioned, "Although research on Happify is limited, interventions based on positive psychology principles have shown potential in improving mood and psychological well-being."
As the variety of digital tools for supporting mental health increases, it’s important not to replace therapy and medication just yet.
"While these apps have demonstrated effectiveness in studies, they are not meant to replace professional treatment for depression," Hafeez explained. "People with depression should consult a healthcare provider to explore the best treatment options for their needs. Furthermore, ongoing research is necessary to fully assess the efficacy and long-term impact of digital interventions for depression."
