
With Omicron cases rapidly increasing across the U.S., the Centers for Disease Control and Prevention has reduced the isolation period from 10 days to five days for individuals testing positive for COVID-19, provided they show no symptoms. Following the initial five days of isolation, it is advised to continue wearing a mask around others for another five days.
The CDC’s announcement on Monday highlighted that this adjustment is based on scientific evidence showing most SARS-CoV-2 transmission happens early in the infection, typically one to two days before symptoms emerge and two to three days after. CDC Director Dr. Rochelle Walensky emphasized that the updated guidelines “strike a balance between our understanding of viral spread and the protection offered by vaccines and booster shots.”
The reduced isolation period does not imply the virus is less severe. Walensky urges people to “get vaccinated, receive booster doses, wear masks in indoor public spaces in areas with significant or high transmission rates, and test before gatherings.” Below are the CDC’s current isolation guidelines based on various factors.
Steps to Take After Testing Positive for COVID-19
If you receive a positive COVID-19 test result, regardless of your vaccination status, you must isolate for at least five days.
If you are not experiencing symptoms
In the absence of symptoms, or if symptoms subside after five days, you may end isolation but should wear a mask for an additional five days to reduce the risk of spreading the virus to others.
If you are experiencing symptoms
The CDC’s latest update did not specify the isolation duration for individuals still experiencing symptoms. Previously, the CDC recommended a 10-day isolation period for those with symptomatic COVID-19.
Upon noticing symptoms (listed by the CDC here), you should quarantine immediately until a negative test confirms the symptoms are not linked to COVID-19.
Steps to Take After Exposure to Someone with COVID-19
If you are fully vaccinated
For individuals who have either (1) received a booster, (2) completed the primary Pfizer or Moderna vaccine series within the past six months, or (3) completed the primary J&J vaccine series within the last two months:
Wear a mask when around others for a period of 10 days.
Get tested five days after exposure, regardless of whether symptoms are present. (If symptoms develop, take a test and remain at home.)
If you are not fully vaccinated
For individuals who either (1) completed the primary Pfizer or Moderna vaccine series over six months ago without a booster, (2) completed the primary J&J vaccine series more than two months ago without a booster, or (3) are unvaccinated:
Remain at home for five days. Test on the fifth day, if possible.
After isolation, continue wearing a mask around others for an additional five days.
If quarantine is not possible, wear a mask for 10 days.
How to Calculate Your Isolation Period
To determine your 10-day isolation and masking timeline: Day “zero” is the initial day symptoms appear, as outlined by the CDC earlier this month. Day “one” is the first full day after symptoms begin.
Get Your Booster Shot
If the news feels overwhelming, keep in mind that vaccines remain effective against Omicron—though receiving a booster is crucial. While Omicron appears more contagious than earlier variants, emerging data suggests it may result in milder illness. However, vaccines and prior infections offer less protection against Omicron compared to previous strains. Refer to the CDC’s booster guide if you haven’t gotten yours yet.
