Buzz
Phosphatidylserine may sound complex, but its impact on brain function is profound. Research highlights two key roles of phosphatidylserine in the brain: it revitalizes brain cell membranes and boosts acetylcholine levels, a neurotransmitter crucial for memory and retrieving information in aging brains [Source: Cenacchi, Crook, Schreiber].
Phosphatidylserine helps rejuvenate brain cell membranes, enhancing memory, focus, mood, and attention span. It is often recommended for memory loss, cognitive decline, depression, and ADHD. Athletes also use it to reduce stress responses and improve performance. Animal studies suggest it may suppress demyelination [Source: Maggioni, Schreiber, Delwaide, Monteleone, Benton, Yamazaki, Monastra].
Phosphatidylserine is a fat-soluble phospholipid essential for brain cell function. As we age, its natural production declines, leading to memory and cognitive issues. Supplementing with phosphatidylserine can help restore some of these declining functions.
Foods like soybeans, egg yolks, chicken, and beef liver contain phosphatidylserine. However, aging and gastrointestinal stress limit the body's ability to absorb enough from food. A therapeutic dose of 100 mg, taken 2-3 times daily, can improve memory and cognitive function within 6 weeks for those with impairments [Source: NMCD, Delwaide].
Initial studies on phosphatidylserine utilized bovine brain cortex. Due to concerns about disease transmission from animals, it is now sourced from soy or cabbage. Research on plant-based phosphatidylserine, such as soy or cabbage, confirms the beneficial effects previously observed with bovine-derived phosphatidylserine [Source: Blokland].
Phosphatidylserine is generally well-tolerated, with minimal side effects. In rare cases, higher doses may cause mild gastrointestinal discomfort or sleep disturbances [Source: NMCD].
