Top 6 Laxatives to Effectively Treat Constipation Today

Forlax Medication contains high-molecular-weight macrogol (4000), a compound that helps relieve constipation by increasing the water content in stools. This action makes the stool softer and increases its bulk, gradually taking effect within 24–48 hours. Macrogol is not absorbed into the bloodstream nor metabolized in the body. This medication is used to treat constipation in adults and children aged 8 years and older.

Forlax 10g is manufactured by Beaufour Ipsen.

Active Ingredient: Macrogol 4000: 10.00g, Citrus (orange-grapefruit) flavor: 0.15g, Sodium Saccharin: 0.017g
Uses:

• For treating symptomatic constipation in adults and children aged 8 years and older.
• Before treatment, underlying disorders should be excluded. For children, Forlax 10g is a temporary solution for constipation, best used with a suitable diet and hygiene practices, and treatment should not exceed 3 months. If symptoms persist despite a proper diet and lifestyle, further medical investigation is necessary.

Contraindications:

• Severe inflammatory bowel diseases (ulcerative colitis, Crohn's disease) or toxic megacolon.
• Gastrointestinal perforation or risk of perforation.
• Intestinal obstruction or suspected obstruction, symptomatic intestinal narrowing.
• Unexplained abdominal pain syndrome.
• Hypersensitivity to the active ingredient or any of the excipients.

Time to take effect: 24–48 hours
Maximum treatment duration: 3 months
Directions for use: Dissolve completely in a glass of water and drink directly.

PediaPEG is widely recognized for its ability to relieve long-term constipation, promoting better digestive system function and improving absorption capabilities in children. PediaPEG is manufactured by Pediatrica, Italy.

Active Ingredient: Each PediaPEG sachet contains 6.563g of Polyethylene Glycol 3350 (PEG 3350).

Uses: For chronic constipation and irregular bowel movements.

Contraindications: PediaPEG should not be used by individuals with:

• Intestinal obstruction.
• Gastrointestinal perforation.
• Intestinal narrowing.
• Allergy to PediaPEG.

Directions for Use: Dissolve one sachet in 62.5ml of water (plain water, orange juice, milk, etc.). The dose can be divided into smaller portions and should be prepared just before use.

Peginpol Laxative Powder for Children is a health supplement suitable for children aged 6 months and older who suffer from constipation. It helps soften stools and stimulates easier bowel movements. Peginpol is a product of the Buona brand, manufactured in Italy.

Active Ingredient: Each 100 grams of Peginpol powder for suspension contains 98.658 grams of Polyethylene Glycol 3350, along with excipients such as sodium saccharin, silicon dioxide, and food flavorings.

Uses: Peginpol is used for treating functional constipation in young children. It works by softening stools, regulating colonic motility, and promoting natural bowel movements in line with the body’s physiological processes.

Effect Time: Results typically appear after 3-6 days.

Directions: Mix one 5g sachet of Peginpol with 70ml of water, or use 2g (one teaspoon) mixed with 25ml of water. It can be prepared in advance and stored in the fridge for multiple uses throughout the day.

Constipass is a powerful laxative solution designed to effectively manage and control constipation in both children and adults. Manufactured by SIIT, a leading pharmaceutical company in Italy with 50 years of experience, Constipass is highly trusted in treating this condition.

Active Ingredients: Each Constipass sachet contains:

• Each double sachet has 13.125g of Macrogol 3350.
• Two single sachets containing 6.65g of Macrogol 3350 (PEG 3350).
• Excipients: Silicon dioxide, flavorings, sodium saccharin.

This active ingredient is recognized for its high efficacy and safety, endorsed by global health organizations such as the European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the UK's National Institute for Health and Care Excellence (NICE).

Uses:

• For treating chronic constipation and irregular bowel movements, and for the prevention and management of constipation.
• Used for pre- and post-surgery care for hemorrhoid treatments.
• Helps older adults with diminished bowel function due to underlying medical conditions.

Effect Time: 1–4 hours.

Advantages over Lactulose-based Laxatives:

Composition:

• Macrogol 3350-based medication: Polyethylene glycol chains that are biologically inert, which means they do not ferment, metabolize, or get absorbed, and are completely excreted in stool.
• Lactulose-based medications: A synthetic disaccharide that, while not absorbed in the intestines, is fermented by bacteria in the colon, producing gases such as CO2 and NH4+.

Mechanism of Action:

• Constipass with Macrogol 3350 uses only the available water when the medication is dissolved or water already present in the intestines, avoiding electrolyte imbalances and gut microbiota disruption, thus minimizing bloating or indigestion.
• In contrast, lactulose attracts water into the intestines, which can lead to water-electrolyte imbalances if used long-term and cause bloating and discomfort due to fermentation gases.

Effectiveness and Safety:

• Macrogol 3350 in Constipass is safe and generally free from the discomforts like bloating, flatulence, or dehydration seen with Lactulose.
• Constipass can be used long-term.
• Constipass leads to higher frequency of bowel movements per week compared to Lactulose (supported by recommendations from the European Digestive Health Organization).

Macrogol 3350 Advantages over Macrogol 4000-based Products:

• Macrogol 3350 in Constipass has a lower molecular weight, meaning it can draw more water at the same dose, acting faster.
• Macrogol 4000-based products require larger doses to achieve the same effect.

Target Audience:

• Constipass: Suitable for children from 6 months of age.
• Macrogol 4000-based products: For children aged 8 and above.

Effect Time:

• Macrogol 3350 products: 1–4 hours.
• Macrogol 4000 products: 24–48 hours.

Constipass is safe for all users, including children, pregnant women, and breastfeeding mothers. The product is available in powder form with a pleasant taste, making it easy for children to take. Many parents report great results.

Directions for Use:

• One single sachet should be mixed with 62.5ml of water.
• Double sachets should be mixed with 125ml of water.

Where to Buy: Constipass is available at hospitals, clinics, and over 300 pharmacies nationwide, including prominent locations like the Central Children's Hospital, Nhi Dong 2 in Ho Chi Minh City, and Viet Duc Hospital. It is also available online at: https://www.facebook.com/Constipassvuotquataobon
Or Call Hotline: 0969.138.181

When discussing constipation treatment, Novolax is a must-mention product.

Novolax contains natural soluble fiber. Upon entering the digestive system, Novolax doesn't dissolve in water but absorbs it, forming a gel-like mixture that increases volume, softens, and aerates stools. When it reaches the large intestine, it becomes food for beneficial gut bacteria, boosting the population of beneficial bacteria in the colon by 50 times. These beneficial bacteria ferment the soluble fiber in the colon, producing gases and byproducts such as short-chain fatty acids: lactic acid, acetic acid, various vitamins, and nutrients. It also creates a mildly acidic environment (pH~5.9), preventing harmful gut bacteria from growing, protecting the digestive system, and strengthening immunity by increasing beneficial bacteria levels.

This process helps reduce constipation effectively while nourishing the gut microbiome, promoting digestive health. Novolax is suitable for adults, children, pregnant women, and breastfeeding mothers.

Novolax has 2 variants:

• Novolax Drops specifically helps with constipation in children from 6 months old.
• Novolax Syrup is suitable for adults, pregnant and postpartum women, those with constipation-related hemorrhoids, and children from 1 year old.

In 10ml of Novolax Syrup contains:

• Fructose oligosaccharide (FOS): 2000mg
• Plum juice powder: 100mg
• Oat extract: 50mg
• Apple pectin: 50mg

In 5ml of Novolax Drops contains:

• Polydextrose: 3000mg
• Plum juice powder: 150mg
• Oat extract: 75mg
• Apple pectin: 25mg

Common benefits of Novolax:

• Provides natural fiber to aid digestion and relieve constipation.
• Nourishes the gut microbiome, promoting digestive health.

Advantages of Novolax:

• Effective within 12-24 hours.
• Comes in an easy-to-use oral syringe, suitable for both children and adults.
• Fruit-flavored sweetness that children enjoy.
• Can be used long-term without reducing effectiveness.

Recommended dosage:

• Children 6 months to 1 year: Start with 2ml/day of Novolax Drops, increasing to 3ml/day if constipation improves slowly.
• Children 1-2 years: 10ml of Novolax Syrup, 1-2 times per day.
• Children over 2 years: 10ml of Novolax Syrup, twice a day.
• Adults, pregnant women, and postpartum women: 10-20ml of Novolax Syrup, 2-3 times per day.

Novolax is manufactured on a GMP-WHO certified production line. It is approved for sale by the Ministry of Health's Food Safety Department and is widely available at pharmacies across the country.

For more details:

Brand website: novolax.com

Affiliated company website: https://novopharm.com.vn/

Facebook fanpage: https://www.facebook.com/Novolax

Duphalac là một loại dung dịch chứa lactulose là thành phần hoạt chất chính, được sử dụng chủ yếu để điều trị táo bón bằng cách tăng khối lượng chất trong ruột lớn. Ngoài ra, thuốc cũng được sử dụng để phòng ngừa và điều trị bệnh não gan ở người lớn. Thuốc Duphalac được sản xuất bởi công ty Abbott Biologicals B.V.

Thành phần hoạt chất: Lactulose 667g/l (667g lactulose trong 1000ml).

Công dụng:

• Ðiều trị táo bón giúp điều hòa nhu động sinh lý của đại tràng.
• Hậu phẫu vùng hậu môn, trực tràng và điều trị bệnh trĩ: Trong trường hợp này thì phân mềm hơn có lợi ích cho người bệnh, giảm nguy cơ xuất huyết.
• Điều trị bệnh lý não gan: Điều trị và phòng ngừa nguy cơ hôn mê gan hay trường hợp tiền hôn mê gan.

Chống chỉ định không nên dùng cho bệnh nhân:

• Có phản ứng quá mẫn với lactose hoặc với bất cứ thành phần nào khác của thuốc.
• Khi bị rối loạn chuyển hóa đường glactose máu.
• Trường hợp tắc nghẽn dạ dày ruột, thủng tiêu hóa hoặc có nguy cơ thủng tiêu hóa.
• Thận trọng khi sử dụng: Trong các trường hợp đau bụng không rõ nguyên nhân, không đỡ sau vài ngày điều trị, những bệnh nhân tiền sử không dung nạp lactose nên dùng dung dịch uống Duphalac nên cẩn trọng.

Thời gian tác dụng của thuốc: Khoảng 1 – 3 ngày.

Hướng dẫn sử dụng: Uống trực tiếp hoặc pha loãng theo chỉ dẫn của bác sĩ. Mỗi liều thuốc nên được dùng trong một lần và không giữ thuốc trong miệng lâu.