Discover the Top 6 Uses and Dosages of Lopran

Lopran is a medication used to treat acute diarrhea, containing Loperamide hydrochloride as its main component. Loperamide is employed to alleviate symptoms in cases of acute diarrhea of unknown origin and some instances of chronic diarrhea. It binds to opioid receptors in the intestine, reducing mucosal irritation and the stimuli causing contraction of the gastrointestinal tract. This is a synthetic opioid that, when taken at normal doses, has minimal effects on the central nervous system.

Details about Lopran:

• Pharmaceutical group: Gastrointestinal drugs
• Dosage form: Hard capsules
• Packaging: Box of 10 blister packs x 10 capsules, box of 1 blister pack x 10 capsules

Lopran is contraindicated in the following cases:

• Individuals with a history of sensitivity to the active ingredient Loperamide hydrochloride or any component of the medication
• Individuals with a history of or currently suffering from acute colitis or pseudomembranous colitis due to the effects of broad-spectrum antibiotics
• Patients with acute dysentery accompanied by high fever and bloody stools
• Patients with intestinal inflammation due to bacterial invasion
• Patients undergoing treatment for acute colonic ulcers
• Individuals with acute infectious diarrhea caused by the presence of highly motile and invasive bacteria in the intestinal mucosa. These include: Shigella, E.coli, Salmonella
• Patients with severe liver failure
• Children under 12 years old and elderly individuals
• It is necessary to avoid the process of inhibiting bowel peristalsis

Patients should discontinue the use of Lopran if constipation, bowel obstruction, or abdominal distention occurs during treatment.

Lopran has the following functions:

• Alleviating symptoms of non-specific acute diarrhea, chronic diarrhea due to intestinal inflammation
• Treating symptoms caused by acute diarrhea in adult patients and children over 12 years old
• Reducing stool volume in patients who have undergone colostomy surgery
• Treating symptoms of acute diarrhea episodes with the involvement of irritable bowel syndrome in adult patients over 18 years old undergoing preliminary examination and diagnosis by a physician.

During the use of Lopran, patients may experience one of the following side effects:

• Dry mouth
• Upper abdominal pain
• Constipation
• Drowsiness
• Body fatigue
• Dizziness
• Skin rash

Patients should discontinue the use of Lopran if experiencing any of the aforementioned side effects or if other unusual symptoms occur. Additionally, to ensure safety, patients should promptly seek medical attention at the hospital. Inform your specialist doctor immediately about your current health condition. At that point, physicians will conduct examinations and determine appropriate solutions.

Lopran hard capsules are administered orally. When necessary, patients should take Lopran with at least 240ml of water. Taking Lopran with plenty of water helps reduce intestinal irritation. Patients should swallow the capsule whole to ensure the therapeutic effect of the product. Do not chew before swallowing. Do not crush or break the structure of the product before use.

Depending on the age, health status, specific conditions, and individual responsiveness, the dosage of Lopran varies among individuals.

Dosage of Lopran in the treatment of acute diarrhea

• For adults
  • Initial dose: 4mg per dose. Then use 2mg per dose when diarrhea is just starting
  • Maximum dose: 16mg per day.
• For children aged 8-12
  • First day (initial dose): 2mg per dose x 3 times a day
  • Second day: 1mg per 10kg after having loose stools
  • Maximum dose: 6mg per day.
• For children aged 6-8
  • First day (initial dose): 2mg per dose x 2 times a day
  • Second day: 1mg per 10kg after having loose stools
  • Maximum dose: 6mg per day.

Dosage of Lopran in the treatment of chronic diarrhea

• For adults
  • Recommended dose: 4 - 8mg per day. Use once or divide into multiple doses.
• For children
  • The dosage of Lopran in children for the treatment of chronic diarrhea has not been studied.

Before and during the use of Lopran, patients should exercise caution with the following:

• Lopran is not recommended for children under 12 years old. Therefore, patients should only use it when absolutely necessary and upon the request of a specialist doctor.
• Women who are breastfeeding should exercise caution before deciding to use Lopran. Because the excipients in the product have the potential to cross the placenta, affecting the development and health of the fetus. Therefore, patients should only use Lopran upon the request of a doctor. Additionally, before initiating treatment with Lopran, pregnant women should carefully weigh the benefits and risks.
• In patients with diarrhea, electrolyte loss may occur. In cases of electrolyte loss, electrolyte replacement therapy and fluid replacement are the most important measures to be applied.
• For patients with acute diarrhea, if there is no clinical improvement within 48 hours, patients should not continue using Imodium. Instead of continuing Lopran, patients should be examined and reconsider the cause of diarrhea.
• For patients with liver dysfunction, during the use of Lopran, patients need to regularly visit the hospital for monitoring. Additionally, patients need to be closely monitored for signs of central nervous system toxicity due to phase 1 metabolism.
• During the treatment of diarrhea with Lopran, AIDS patients must discontinue use if they notice any abnormal symptoms or the earliest symptoms such as abdominal distension.