CLR Error 80004005 prevents you from starting your computer or using applications on Windows 10/11.

1. Causes of CLR Error 80004005
CLR Error 80004005 commonly originates in Windows 10/11 and can stem from various reasons. It could result from operating system errors or application issues. However, in some cases, they have identified the root cause of CLR 80004005 error on Windows computers.

Most instances of encountering CLR 80004005 error on a computer stem from the .NET framework. Specifically, the issue arises when the computer has multiple .NET framework software installed. The presence of more than one .NET framework software can lead to various errors, particularly the CLR 80004005 code on the computer. Fortunately, this error is not overly severe and can be easily addressed.
2. How to fix CLR error 80004005 on Windows computers
Utilize the .NET Framework Repair Tool on your computer
Microsoft provides users with a pre-built tool for fixing errors on computers, and you only need to download them. Below is how to fix CLR Error 80004005 on computers using Microsoft's error repair tool.
Homepage: .NET Framework Repair Tool
Step 1: Visit the .NET Framework Repair Tool homepage and select the Download section to download the software to your computer.

Step 2: Next, proceed to install the software similar to other programs for use. Simply accept the agreements and press Next to complete the process.

Step 3: During the software installation, the system will automatically fix errors by intervening with Reregister on the computer and restarting Windows services. Just press Next for them to handle it automatically.

Step 4: Once the software is successfully installed, simply press Finish to conclude and check the features on the computer to see if CLR Error 80004005 still persists.

Reinstalling .NET Framework on the computer
In urgent cases, you can also reinstall NET Framework on the computer to quickly and effectively fix the error.
Homepage: NET Framework
Step 1: Visit the NET Framework official website and select Download to download the software to your computer.

Step 2: Currently, there are various versions of NET Framework, but it is advisable to install the latest version for stable performance. Choose Download .NET runtime.

Step 3: Depending on your device, select the appropriate version. If using a desktop computer, download the Run desktop apps package and choose the suitable version.
Generally, modern computers use x64, so download this version. If your computer uses x86 or ARM64, select the corresponding version.

Step 4: Once the software is successfully installed, simply press Finish to conclude and check the features on the computer to see if CLR error 80004005 still persists.

Uninstalling and Reinstalling Software on the Computer
In addition to the above methods, you can also choose to uninstall the software and reinstall it from scratch to ensure compatibility with NET Framework. Typically, CLR 80004005 errors can be resolved using this approach.
Step 1: Open the Start Menu and type Control Panel to access the management settings on your computer.

Step 2: Next, select the Programs tab and choose Programs and Features to initiate the scrutiny of applications on your computer.

Step 3: Locate the applications encountering CLR Error 80004005 on the computer and choose Uninstall to remove them.
Once completed, restart your computer and reinstall the software for optimal results.

In this article, Software Tricks has guided you on how to handle CLR Error 80004005 on Windows 10/11 computers. Wishing you success!